Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21963548 | 0.84 | KDM4E (0.39) | RAPGEF4HTR6JAK2BTK | |
| SCHEMBL28606804 | 0.83 | KMT2A (0.38) | HTR6HTR2A | |
| SCHEMBL28852705 | 0.83 | FABP4 (0.45) | RAPGEF4HTR6FABP4DRD2HTR2A | |
| SCHEMBL23668185 | 0.80 | PIK3C3 (0.33) | RAPGEF4KLK7 | |
| SCHEMBL28604695 | 0.79 | ANPEP (0.35) | JAK2BTKCTSG | |
| SCHEMBL28473997 | 0.79 | JAK2 (0.36) | RAPGEF4HTR6JAK2BTKKLK7 | |
| SCHEMBL31465621 | 0.77 | RAPGEF4 (0.36) | RAPGEF4JAK2BTKFABP4CTSG | |
| SCHEMBL23403832 | 0.77 | RAPGEF4 (0.36) | RAPGEF4JAK2BTKFABP4CTSG | |
| SCHEMBL28478032 | 0.75 | JAK2 (0.33) | RAPGEF4JAK2BTK | |
| SCHEMBL28802486 | 0.73 | PIK3C3 (0.48) | RAPGEF4FABP4CTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166094-A | Novel compounds as protein kinase inhibitors and pharmaceutical compositions comprising the same | 怡诺安有限公司 | 2021-07-23 | — | — | CN | disclosed |