Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21963617 | 0.90 | LMNA (0.70) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| SCHEMBL21963620 | 0.88 | KMT2A (0.67) | KMT2ATDP1LMNAHDAC1ALDH1A1 | |
| SCHEMBL21963607 | 0.83 | ALDH1A1 (0.68) | KMT2ATDP1HTTALDH1A1MAPK1 | |
| Benzyl Nicotinate SCHEMBL29394048 | 0.83 | LMNA (1.00) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| Benzyl Nicotinate SCHEMBL24600 | 0.83 | LMNA (1.00) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| SCHEMBL22015262 | 0.83 | KMT2A (0.74) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| SCHEMBL22014585 | 0.82 | KMT2A (0.78) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| SCHEMBL21963616 | 0.82 | LMNA (0.65) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| Benzyl Nicotinate SCHEMBL29080664 | 0.82 | LMNA (0.97) | KMT2ATDP1LMNASLC6A2SLC6A3 | |
| Benzyl Nicotinate SCHEMBL28041943 | 0.82 | LMNA (0.97) | KMT2ATDP1LMNASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220009892-A1 | SUBSTITUTED PYRIDINE CARBOXYLIC ACIDS, THEIR PREPARATION METHOD AND COMPOSITIONS THEREOF | INCILIA THERAPEUTICS PRIVATE LIMITED (IN) | 2022-01-13 | — | — | US | disclosed |
| US-20220009892-A1 | SUBSTITUTED PYRIDINE CARBOXYLIC ACIDS, THEIR PREPARATION METHOD AND COMPOSITIONS THEREOF | INCILIA THERAPEUTICS PRIVATE LIMITED (IN) | 2022-01-13 | — | — | US | disclosed |
| WO-2020100169-A1 | SUBSTITUTED PYRIDINE CARBOXYLIC ACIDS, THEIR PREPARATION METHOD AND COMPOSITIONS THEREOF | INCILIA THERAPEUTICS PRIVATE LIMITED (IN) | 2020-05-22 | — | — | WO | disclosed |
| WO-2020100169-A1 | SUBSTITUTED PYRIDINE CARBOXYLIC ACIDS, THEIR PREPARATION METHOD AND COMPOSITIONS THEREOF | INCILIA THERAPEUTICS PRIVATE LIMITED (IN) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009892-A1 | SUBSTITUTED PYRIDINE CARBOXYLIC ACIDS, THEIR PREPARATION METHOD AND COMPOSITIONS THEREOF | PC, PCCA, GLS2 | KMT2A 2224/4885TDP1 4115/4885LMNA 3457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.