Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10879701 | 0.80 | SLC6A4 (0.47) | — | |
| SCHEMBL28988665 | 0.80 | ESR2 (0.55) | ALDH1A1KDM4ESMN1; SMN2HSD17B10ALDH5A1 | |
| SCHEMBL16691392 | 0.80 | KMT2A (0.40) | SMN1; SMN2CYP2A6 | |
| SCHEMBL436575 | 0.80 | SLC6A3 (0.47) | — | |
| SCHEMBL19056924 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33 | |
| SCHEMBL661791 | 0.78 | KMT2A (0.41) | SMN1; SMN2CYP2A6TDP1 | |
| SCHEMBL1334287 | 0.78 | ESR2 (0.54) | ALDH1A1KDM4ESMN1; SMN2HSD17B10ALDH5A1 | |
| Hydrochloric Acid SCHEMBL28583230 | 0.78 | OPRM1 (0.44) | — | |
| SCHEMBL6498103 | 0.78 | HDAC4 (0.44) | ALDH1A1HSD17B10 | |
| SCHEMBL4770412 | 0.78 | LIG1 (0.37) | ALDH1A1KDM4ESMN1; SMN2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643703-A1 | EP300/CREBBP INHIBITOR | Daiichi Sankyo Co., Ltd. (JP) | 2020-04-29 | — | — | EP | disclosed |