Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16691392 | 0.98 | KMT2A (0.40) | KMT2ASMN1; SMN2CYP2A6POLBHSD11B1 | |
| SCHEMBL27925710 | 0.96 | CYP2A6 (0.38) | KMT2ASMN1; SMN2CYP2A6POLBHSD11B1 | |
| SCHEMBL8290260 | 0.91 | CYP2A6 (0.41) | KMT2ASMN1; SMN2CYP2A6MAOBMAOA | |
| SCHEMBL19031250 | 0.79 | OPRM1 (0.39) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4770412 | 0.79 | LIG1 (0.37) | KMT2ASMN1; SMN2CYP2A6POLBMAOB | |
| SCHEMBL1334287 | 0.79 | ESR2 (0.54) | KMT2ASMN1; SMN2HSD11B1PDE4APDE4B | |
| SCHEMBL6498103 | 0.79 | HDAC4 (0.44) | HSD11B1 | |
| SCHEMBL21964328 | 0.79 | SLC6A4 (0.47) | CYP2A6MAOBMAOAPDE4APDE4B | |
| SCHEMBL1152247 | 0.78 | AKR1C1 (0.47) | — | |
| SCHEMBL21964313 | 0.78 | ALDH1A1 (0.41) | SMN1; SMN2CYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435390-B1 | TRANSALKYLATION OF POLYCYCLOHEXYLBENZENES | EXXONMOBIL CHEM PATENTS INC (US) | 2016-08-17 | — | — | EP | disclosed |
| US-9045486-B2 | Pyrimidone derivatives and their use in the treatment, amelioration or prevention of a viral disease | SAVIRA PHARMACEUTICALS GMBH (AT) | 2015-06-02 | — | — | US | disclosed |
| US-20140194431-A1 | PYRIMIDONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE | SAVIRA PHARMACEUTICALS GMBH (AT) | 2014-07-10 | — | — | US | disclosed |
| US-8633343-B2 | Transalkylation of polycyclohexylbenzenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-01-21 | — | — | US | disclosed |
| US-20120046499-A1 | Transalkylation of Polycyclohexylbenzenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-02-23 | — | — | US | disclosed |
| WO-2010138248-A2 | TRANSALKYLATION OF POLYCYCLOHEXYLBENZENES | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046499-A1 | Transalkylation of Polycyclohexylbenzenes | FOSB, TMSB10, ACLY | KMT2A 1640/4885SMN1; SMN2 4808/4885CYP2A6 2553/4885 |
| US-20140194431-A1 | PYRIMIDONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE | TPMT, XDH, DPYD | KMT2A 4787/4885SMN1; SMN2 1267/4885CYP2A6 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.