Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.82 |
| ▸ | LMNA | P02545 | 7/20 | 0.82 |
| ▸ | RAB9A | P51151 | 6/20 | 0.82 |
| ▸ | NPC1 | O15118 | 5/20 | 0.82 |
| ▸ | USP2 | O75604 | 3/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.82 |
| ▸ | GAA | P10253 | 1/20 | 0.82 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21535885 | 0.78 | RAB9A (0.78) | ALDH1A1LMNARAB9ANPC1USP2 | |
| SCHEMBL21536505 | 0.77 | RAB9A (1.00) | ALDH1A1LMNARAB9ANPC1USP2 | |
| SCHEMBL21536261 | 0.73 | SCD5 (0.72) | ALDH1A1LMNARAB9ANPC1USP2 | |
| SCHEMBL15752125 | 0.71 | HTR2A (0.64) | ALDH1A1LMNARAB9ANPC1USP2 | |
| SCHEMBL21536275 | 0.69 | SCD5 (0.95) | ALDH1A1LMNARAB9ANPC1USP2 | |
| SCHEMBL21536507 | 0.69 | SCD5 (0.78) | ALDH1A1LMNARAB9ANPC1USP2 | |
| SCHEMBL21523598 | 0.68 | SCD5 (1.00) | ALDH1A1LMNARAB9ANPC1USP2 | |
| SCHEMBL21536253 | 0.68 | SCD5 (0.70) | ALDH1A1LMNARAB9ANPC1USP2 | |
| SCHEMBL31023878 | 0.68 | CACNA2D1 (0.65) | KDM4EHPGDKMT2AMAPTMEN1 | |
| SCHEMBL31350717 | 0.68 | MAOB (0.80) | ALDH1A1LMNAUSP2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200138829-A1 | METHODS OF CANCER TREATMENT | Ferro Therapeutics, Inc. | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200138829-A1 | METHODS OF CANCER TREATMENT | AIFM2, GPX4, DDIT3 | ALDH1A1 1395/4885LMNA 2992/4885RAB9A 3332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.