Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.83 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.83 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.83 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.83 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.83 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.83 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.83 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.83 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.83 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.83 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.83 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichostatin SCHEMBL446806 | 0.91 | HDAC1 (1.00) | HDAC1HDAC6HDAC4HDAC8HDAC3 | |
| Trichostatin SCHEMBL675951 | 0.91 | HDAC1 (1.00) | HDAC1HDAC6HDAC4HDAC8HDAC3 | |
| Trichostatin SCHEMBL16380793 | 0.91 | HDAC1 (1.00) | HDAC1HDAC6HDAC4HDAC8HDAC3 | |
| Trichostatin SCHEMBL19886 | 0.91 | HDAC1 (1.00) | HDAC1HDAC6HDAC4HDAC8HDAC3 | |
| Trichostatin SCHEMBL446807 | 0.91 | HDAC1 (1.00) | HDAC1HDAC6HDAC4HDAC8HDAC3 | |
| Trichostatin SCHEMBL29450582 | 0.90 | HDAC1 (0.97) | HDAC1HDAC6HDAC4HDAC8HDAC3 | |
| SCHEMBL1521050 | 0.85 | HDAC1 (0.76) | HDAC1HDAC6HDAC4HDAC8HDAC3 | |
| SCHEMBL3715218 | 0.85 | HDAC1 (0.76) | HDAC1HDAC6HDAC4HDAC8HDAC3 | |
| SCHEMBL1521045 | 0.85 | HDAC1 (0.76) | HDAC1HDAC6HDAC4HDAC8HDAC3 | |
| SCHEMBL1521099 | 0.83 | HDAC1 (0.72) | HDAC1HDAC6HDAC4HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200140456-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140456-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | CRBN, CBL, STUB1 | HDAC1 3523/4885HDAC6 2941/4885HDAC4 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.