SCHEMBL21966433

SCHEMBL21966433

C1=CCC(c2cccc(-c3nc(-c4ccccc4)nc(-c4ccc5c6ccccc6c6ccccc6c5c4)n3)c2)C=C1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
ATM Q13315 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
GLA P06280 1/20 0.32
PDE10A Q9Y233 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
ACP1 P24666 1/20 0.31
PDE5A O76074 2/20 0.30
ABCG2 Q9UNQ0 2/20 0.30
NTSR1 P30989 1/20 0.30
USP2 O75604 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22544933 0.87 MEN1 (0.32) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL18644481 0.86 GP6 (0.35) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL22240888 0.85 LIMK1 (0.31)
SCHEMBL20648201 0.85 MEN1 (0.34) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24907561 0.81 PLA2G2A (0.32) ALDH1A1HPGDKDM4EHSD17B10
SCHEMBL26068382 0.81 ALDH1A1 (0.32) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20392209 0.81 PLA2G2A (0.32)
SCHEMBL24971352 0.81 KDM4E (0.30) ALDH1A1MAPTHPGDATMKDM4E
SCHEMBL24054463 0.81 MEN1 (0.33) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL18866852 0.80 L3MBTL1 (0.38) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200144508-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200144508-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD1, OCIAD2, OR10J3 MEN1 3756/4885KMT2A 3585/4885ALDH1A1 49/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.