SCHEMBL2196845

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2201098	0.84	BRD4 (0.43)	CDC7BRD4IKBKBBTKJAK2
	SCHEMBL2198205	0.84	BRD4 (0.40)	CDC7BRD4IKBKBBTKJAK2
	SCHEMBL2195873	0.84	BRD4 (0.47)	CDC7BRD4IKBKBRAB9AJAK2
	SCHEMBL2196975	0.83	IKBKB (0.47)	BRD4PARP1IKBKBJAK2FFAR1
	SCHEMBL2198463	0.83	BRD4 (0.52)	CDC7BRD4IKBKBBTKJAK2
	SCHEMBL2196863	0.82	CDC7 (0.38)	CDC7BRD4IKBKBJAK2
	SCHEMBL2200693	0.82	PARP1 (0.47)	CDC7BRD4PARP1JAK2FFAR1
	SCHEMBL13446750	0.81	BRD4 (0.39)	CDC7BRD4PARP1IKBKBJAK2
	SCHEMBL4346833	0.81	CDC7 (0.54)	CDC7BRD4PARP1NPC1RAB9A
	SCHEMBL4347544	0.81	BRD4 (0.47)	CDC7BRD4PARP1IKBKBJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.