SCHEMBL2196975

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2198773	0.89	KDM4E (0.44)	IKBKBJAK2BRD4PARP1KDM4E
	SCHEMBL2200763	0.84	JAK2 (0.47)	JAK2BRD4KDM4EALDH1A1LMNA
	SCHEMBL2195873	0.84	BRD4 (0.47)	IKBKBJAK2BRD4KDM4EALDH1A1
	SCHEMBL2198463	0.83	BRD4 (0.52)	IKBKBJAK2BRD4FFAR1
	SCHEMBL2196845	0.83	CDC7 (0.51)	IKBKBJAK2BRD4PARP1FFAR1
	SCHEMBL2198478	0.82	BRD4 (0.46)	BRD4KDM4EALDH1A1
	SCHEMBL4339152	0.81	BRD4 (0.52)	IKBKBJAK2BRD4PARP1FFAR1
	SCHEMBL4347544	0.81	BRD4 (0.47)	IKBKBJAK2BRD4PARP1ABL1
	SCHEMBL2199344	0.80	BRD4 (0.45)	IKBKBBRD4KDM4EALDH1A1LMNA
	SCHEMBL2199667	0.80	BRD4 (0.45)	IKBKBBRD4KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.