SCHEMBL21972686

SCHEMBL21972686

Nc1ccc(-c2ccc(-c3ccc(C4c5c(c6ccccc6c6ccccc56)Oc5c4c4ccccc4c4ccccc54)cc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.45
HSD17B10 Q99714 2/20 0.45
CYP3A4 P08684 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
GLA P06280 1/20 0.39
ALOX15 P16050 1/20 0.39
TP53 P04637 1/20 0.37
MITF O75030 1/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
ATM Q13315 1/20 0.34
KDM1A O60341 3/20 0.33
ACHE P22303 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21971755 0.91 KDM1A (0.40) TAAR1HSD17B10CYP3A4TDP1ALDH1A1
SCHEMBL21971757 0.85 TP53 (0.39) CYP3A4ALDH1A1KDM4EMAPTHPGD
SCHEMBL21972685 0.85 MMP3 (0.44) TDP1NPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL21971029 0.83 ALDH1A1 (0.34) TAAR1HSD17B10ALDH1A1KDM1AMAOB
SCHEMBL21971030 0.83 ACHE (0.33) TAAR1TDP1KDM4EMAPTKDM1A
SCHEMBL21971736 0.83 ALDH1A1 (0.38) TAAR1HSD17B10CYP3A4NPC1RAB9A
SCHEMBL21971699 0.83 KDM1A (0.33) TAAR1TDP1KDM4EMAPTKDM1A
SCHEMBL21971123 0.83 ESR1 (0.41) KDM1AMAOB
SCHEMBL21971768 0.83 ESR1 (0.41) KDM1AMAOB
SCHEMBL21972687 0.82 ALDH1A1 (0.37) HSD17B10CYP3A4NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200144518-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-05-07 US disclosed