Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | UNG | P13051 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199100 | 0.91 | RARB (0.39) | RARBRARARARGUNGMEN1 | |
| SCHEMBL2179294 | 0.91 | KDM4E (0.41) | MAPT | |
| SCHEMBL2199646 | 0.84 | DGAT1 (0.36) | MAPT | |
| SCHEMBL2195168 | 0.83 | DGAT1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL2199101 | 0.83 | ALDH1A1 (0.37) | RARBRARARARGUNGALDH1A1 | |
| SCHEMBL2177806 | 0.82 | TRPV1 (0.44) | RARBRARAMEN1ALDH1A1MAPT | |
| SCHEMBL2199151 | 0.80 | MAPK1 (0.38) | — | |
| SCHEMBL2198291 | 0.79 | TDP2 (0.39) | ALDH1A1 | |
| SCHEMBL2177810 | 0.77 | KDM4E (0.41) | MAPTSPHK1 | |
| SCHEMBL13718891 | 0.76 | PTPN1 (0.44) | MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519500-A1 | INHIBITORS OF DIACYLGLYCEROL ACYL TRANSFERASE | Piramal Healthcare Ltd. (IN) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080718-A1 | INHIBITORS OF DIACYLGLYCEROL ACYL TRANSFERASE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |