Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21974999 | 0.86 | RAB9A (0.43) | RAB9AMAPTPOLBNPSR1KDR | |
| SCHEMBL21974791 | 0.85 | MAPT (0.44) | RAB9AMAPTPOLBNPSR1KDR | |
| SCHEMBL21974929 | 0.84 | ABCG2 (0.41) | RAB9AMAPTPOLBNPSR1ALDH1A1 | |
| SCHEMBL21974789 | 0.82 | RAB9A (0.41) | RAB9AMAPTPOLBNPSR1ADORA3 | |
| SCHEMBL21974945 | 0.76 | MAPT (0.52) | RAB9AMAPTPOLBNPSR1ADORA3 | |
| SCHEMBL21975712 | 0.75 | ALDH1A1 (0.38) | RAB9APOLBNPSR1ALDH1A1MEN1 | |
| SCHEMBL21974793 | 0.72 | KDR (0.39) | MAPTKDRALDH1A1MEN1GAA | |
| SCHEMBL21975143 | 0.70 | MAPT (0.40) | MAPTPOLBNPSR1GAAABCG2 | |
| SCHEMBL21975670 | 0.69 | MAPT (0.40) | RAB9AMAPTPOLBNPSR1ALDH1A1 | |
| SCHEMBL21975132 | 0.68 | MAPT (0.40) | RAB9AMAPTPOLBNPSR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3647313-A1 | SUBSTITUTED ARYL ETHER COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Xiamen University (CN) | 2020-05-06 | — | — | EP | disclosed |