Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | TPO | P07202 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 8/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2981548 | 0.87 | ADORA2A (0.60) | KMT2APOLBADORA2AADORA1HPRT1 | |
| SCHEMBL10506260 | 0.81 | PNP (0.58) | MPOTPOADORA2AADORA1HPRT1 | |
| SCHEMBL5732559 | 0.76 | ADORA2A (0.76) | ADORA2AADORA1USP2CYP1A2CYP3A4 | |
| SCHEMBL21977361 | 0.75 | LMNA (0.69) | MPOTPOKMT2AHPRT1LMNA | |
| SCHEMBL3117339 | 0.74 | ADORA2A (0.62) | KMT2AADORA2AADORA1HPRT1TSHR | |
| SCHEMBL9475856 | 0.74 | HPGD (0.59) | MPOTPOKMT2APOLBALDH1A1 | |
| SCHEMBL21977293 | 0.72 | TP53 (0.42) | POLBADORA2AADORA1USP2CYP1A2 | |
| SCHEMBL21977340 | 0.72 | USP2 (0.38) | MPOTPOKMT2APOLBADORA2A | |
| SCHEMBL21977260 | 0.72 | BRDT (0.41) | MPOTPOKMT2APOLBALDH1A1 | |
| SCHEMBL21977308 | 0.72 | ADORA2A (0.51) | KMT2AADORA2AADORA1USP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11986480-B2 | Heterocyclic compound | TOHOKU UNIVERSITY (JP) | 2024-05-21 | — | — | US | disclosed |
| US-20200163970-A1 | HETEROCYCLIC COMPOUND | TOHOKU UNIVERSITY (JP) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200163970-A1 | HETEROCYCLIC COMPOUND | SQSTM1, BECN1, ATG7 | MPO 3785/4885TPO 4713/4885KMT2A 3485/4885 |
| US-11986480-B2 | Heterocyclic compound | SQSTM1, BECN1, ATG7 | MPO 3785/4885TPO 4713/4885KMT2A 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.