Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | TPO | P07202 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475698 | 0.85 | GRM2 (0.51) | HPGDKMT2AMEN1TSHRPOLB | |
| SCHEMBL30931879 | 0.83 | PDE8B (0.53) | HPGDKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL9477367 | 0.80 | ADORA3 (0.46) | HPGDGAAKMT2AMEN1TSHR | |
| SCHEMBL9476624 | 0.79 | TSHR (0.61) | HPGDPKMKMT2AMEN1TSHR | |
| SCHEMBL9476195 | 0.77 | ADORA3 (0.51) | HPGDKMT2AMEN1TSHRPOLB | |
| SCHEMBL21977361 | 0.77 | LMNA (0.69) | HPGDGAAPKMKMT2AMEN1 | |
| SCHEMBL9476477 | 0.76 | MEN1 (0.62) | HPGDGAAPKMKMT2AMEN1 | |
| SCHEMBL21127684 | 0.75 | HPRT1 (0.40) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL20224894 | 0.75 | ADORA2A (0.46) | HPGDKMT2AALDH1A1 | |
| SCHEMBL21977321 | 0.74 | MPO (0.54) | HPGDKMT2AMEN1TSHRMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204353-A | 3-benzyl-3H-1,2,3-triazolo[4,5-d]pyrimidines, compositions thereof, and method of treating epilepsy therewith | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0288431-B1 | 3H-1,2,3-triazolo[4,5-d]pyrimidines | CIBA-GEIGY AG (CH) | 1992-08-19 | — | — | EP | disclosed |
| EP-0288431-A1 | 3H-1,2,3-triazolo[4,5-d]pyrimidines | CIBA-GEIGY AG (CH) | 1988-10-26 | — | — | EP | disclosed |