Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.49 |
| ▸ | PI4KA | P42356 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204689 | 0.87 | PDE8A (0.60) | CDK1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30532617 | 0.87 | HDAC6 (0.66) | HDAC6HDAC1HDAC4HSP90AA1HSP90AB1 | |
| SCHEMBL21977403 | 0.87 | HDAC6 (0.66) | HDAC6HDAC1HDAC4HSP90AA1HSP90AB1 | |
| SCHEMBL1640041 | 0.85 | PDE4A (0.69) | CDK1CCNB1CCNE1CDK2PDE4A | |
| SCHEMBL23977339 | 0.82 | CDK1 (0.54) | CDK1CCNB1CCNE1CDK2PDE4A | |
| SCHEMBL6659204 | 0.81 | ADORA2A (0.74) | ALDH1A1ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL7206653 | 0.79 | TLR7 (0.51) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9738975 | 0.79 | ADORA2A (0.65) | CDK1CCNB1CCNE1CDK2PDE4A | |
| SCHEMBL15940663 | 0.78 | CDK1 (0.49) | CDK1CCNB1CCNE1CDK2PDE4A | |
| SCHEMBL15941427 | 0.78 | PDE4A (0.51) | CDK1CCNB1CCNE1CDK2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11986480-B2 | Heterocyclic compound | TOHOKU UNIVERSITY (JP) | 2024-05-21 | — | — | US | disclosed |
| US-20200163970-A1 | HETEROCYCLIC COMPOUND | TOHOKU UNIVERSITY (JP) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200163970-A1 | HETEROCYCLIC COMPOUND | SQSTM1, BECN1, ATG7 | CDK1 1828/4885CCNB1 3218/4885CCNE1 3678/4885 |
| US-11986480-B2 | Heterocyclic compound | SQSTM1, BECN1, ATG7 | CDK1 1828/4885CCNB1 3218/4885CCNE1 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.