SCHEMBL21980345

SCHEMBL21980345

CCO[Si](CCCC=C(CS(=O)(=O)c1ccc(C)cc1)C(N)=O)(OCC)OCC

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
KMT2A Q03164 2/20 0.37
RECQL P46063 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
MAPT P10636 4/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD11B1 P28845 1/20 0.34
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PKM P14618 2/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20604832 0.90 ALDH1A1 (0.41) ALDH1A1CA2CA9KMT2ARECQL
SCHEMBL28575031 0.89 ALDH1A1 (0.40) ALDH1A1CA2CA9KMT2ARECQL
SCHEMBL20608661 0.87 ALDH1A1 (0.39) ALDH1A1CA2CA9KMT2ARECQL
SCHEMBL21986231 0.78 ALDH1A1 (0.43) ALDH1A1CA2CA9KMT2ARECQL
SCHEMBL21980344 0.74 ALDH1A1 (0.47) ALDH1A1CA2CA9KMT2ARECQL
SCHEMBL15806073 0.74 ALDH1A1 (0.61) ALDH1A1KMT2AMAPTCYP3A4CYP2C9
SCHEMBL15655348 0.74
SCHEMBL15655993 0.74 TBXAS1 (0.31)
SCHEMBL20608696 0.72 ALDH1A1 (0.41) ALDH1A1CA2CA9KMT2ARECQL
SCHEMBL28268849 0.69 ALDH1A1 (0.51) ALDH1A1CA2CA9KMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12296031-B2 Esthetic dental filling material with high depth of cure IVOCLAR VIVADENT AG (LI) 2025-05-13 US claimed
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress IVOCLAR VIVADENT AG (LI) 2023-08-24 US claimed
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress IVOCLAR VIVADENT AG (LI) 2023-06-13 US claimed
EP-4124331-A1 AESTHETIC DENTAL FILLING MATERIAL WITH HIGH CURING DEPTH Ivoclar Vivadent AG (LI) 2023-02-01 EP claimed
EP-3659575-A1 PHOTOPOLYMERISABLE DENTAL COMPOSITES WITH FAST CURING AND LOW SHRINKAGE STRESS Ivoclar Vivadent AG (LI) 2020-06-03 EP claimed
US-20200165363-A1 PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS IVOCLAR VIVADENT AG (LI) 2020-05-28 US claimed
US-12296031-B2 Esthetic dental filling material with high depth of cure IVOCLAR VIVADENT AG (LI) 2025-05-13 US disclosed
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress IVOCLAR VIVADENT AG (LI) 2023-08-24 US disclosed
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress IVOCLAR VIVADENT AG (LI) 2023-06-13 US disclosed
US-20230052305-A1 Esthetic Dental Filling Material With High Depth Of Cure IVOCLAR VIVADENT AG (LI) 2023-02-16 US disclosed
EP-4124331-A1 AESTHETIC DENTAL FILLING MATERIAL WITH HIGH CURING DEPTH Ivoclar Vivadent AG (LI) 2023-02-01 EP disclosed
EP-3659575-A1 PHOTOPOLYMERISABLE DENTAL COMPOSITES WITH FAST CURING AND LOW SHRINKAGE STRESS Ivoclar Vivadent AG (LI) 2020-06-03 EP disclosed
US-20200165363-A1 PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS IVOCLAR VIVADENT AG (LI) 2020-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress MMAB, ALAD, SULT1E1 ALDH1A1 355/4885CA2 3658/4885CA9 3909/4885
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress MMAB, ALAD, SULT1E1 ALDH1A1 355/4885CA2 3658/4885CA9 3909/4885
US-20200165363-A1 PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS MMAB, ALAD, SULT1E1 ALDH1A1 355/4885CA2 3658/4885CA9 3909/4885
US-12296031-B2 Esthetic dental filling material with high depth of cure RARA, RARG, RARB ALDH1A1 49/4885CA2 3940/4885CA9 2079/4885
US-20230052305-A1 Esthetic Dental Filling Material With High Depth Of Cure RARA, RARG, RARB ALDH1A1 49/4885CA2 3940/4885CA9 2079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.