Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 18/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 18/20 | 0.46 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19773850 | 0.81 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL17382579 | 0.74 | TP53 (0.46) | HCRTR1HCRTR2POLL | |
| SCHEMBL17376705 | 0.74 | HCRTR2 (0.43) | HCRTR1HCRTR2POLL | |
| SCHEMBL19773817 | 0.72 | HCRTR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL19773914 | 0.71 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL23256884 | 0.70 | MCL1 (0.42) | — | |
| SCHEMBL28476476 | 0.70 | KMT2A (0.45) | HCRTR1HCRTR2POLL | |
| SCHEMBL11224539 | 0.68 | CRHBP (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL4536295 | 0.68 | PDE4A (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL11229583 | 0.68 | HCRTR1 (0.39) | HCRTR1HCRTR2POLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160950-B1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | disclosed |