Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18468481 | 0.91 | LTA4H (0.46) | SIGMAR1MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL19465230 | 0.87 | CHRNA7 (0.43) | SIGMAR1MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL14461599 | 0.82 | LMNA (0.53) | HTR1AADRA1AMEN1RAB9AKMT2A | |
| SCHEMBL27382395 | 0.82 | TSHR (0.40) | MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL12653997 | 0.79 | TSHR (0.42) | HTR1AADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL18951276 | 0.79 | SLC1A1 (0.42) | SIGMAR1MEN1KMT2ACYP1A2SLC6A2 | |
| SCHEMBL29058874 | 0.79 | ALDH1A1 (0.48) | LMNA | |
| SCHEMBL30488988 | 0.79 | ALDH1A1 (0.48) | LMNA | |
| SCHEMBL7850044 | 0.78 | TSHR (0.43) | SIGMAR1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL14118736 | 0.78 | BCHE (0.46) | HTR1AMEN1KMT2ASMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240413-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-13 | — | — | EP | disclosed |
| CN-109476676-A | Optical activity pyrans and chromene base phenol derivatives and the pharmaceutical composition comprising it | 格拉斯如睦株式会社 | 2019-03-15 | — | — | CN | disclosed |