Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302948 | 0.85 | GPR174 (0.54) | HCAR3MAPTMAPK1MEN1KMT2A | |
| SCHEMBL9302938 | 0.85 | GPR174 (0.54) | HCAR3MAPTMAPK1MEN1KMT2A | |
| SCHEMBL22716724 | 0.83 | HCAR3 (0.42) | HCAR3MAPTMAPK1MEN1KMT2A | |
| SCHEMBL22716726 | 0.83 | HCAR3 (0.42) | HCAR3MAPTMAPK1MEN1KMT2A | |
| SCHEMBL28702278 | 0.83 | HCAR3 (0.42) | HCAR3MAPTMAPK1MEN1KMT2A | |
| SCHEMBL29525723 | 0.83 | MAPT (0.56) | HCAR3MAPTMAPK1MEN1KMT2A | |
| SCHEMBL17896593 | 0.83 | MAPT (0.56) | HCAR3MAPTMAPK1MEN1KMT2A | |
| SCHEMBL18425295 | 0.83 | ALDH1A1 (0.52) | MAPTMAPK1MEN1KMT2AL3MBTL1 | |
| SCHEMBL22495122 | 0.81 | HCAR3 (0.59) | HCAR3MAPTMAPK1L3MBTL1PKM | |
| SCHEMBL20338334 | 0.81 | MEN1 (0.58) | HCAR3MAPTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328859-B1 | 3-((4-ISOQUINOLIN-3-YL)METHYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV) | BOEHRINGER INGELHEIM INT (DE) | 2020-06-03 | — | — | EP | disclosed |