SCHEMBL21986386

SCHEMBL21986386

CCc1cc(Cl)cc(C(=O)O)c1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
HPGD P15428 1/20 0.53
HSD17B10 Q99714 1/20 0.53
CYP3A4 P08684 1/20 0.52
GABRP O00591 2/20 0.46
GABRD O14764 2/20 0.46
GABRA1 P14867 2/20 0.46
GABRB1 P18505 2/20 0.46
GABRG2 P18507 2/20 0.46
GABRB3 P28472 2/20 0.46
GABRA5 P31644 2/20 0.46
GABRA3 P34903 2/20 0.46
GABRA2 P47869 2/20 0.46
GABRB2 P47870 2/20 0.46
GABRA4 P48169 2/20 0.46
GABRE P78334 2/20 0.46
GABRA6 Q16445 2/20 0.46
GABRG1 Q8N1C3 2/20 0.46
GABRG3 Q99928 2/20 0.46
GABRQ Q9UN88 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12747377 0.85 ALDH1A1 (0.53) ALDH1A1HPGDHSD17B10CYP3A4AKR1C4
SCHEMBL28761699 0.84 ALDH1A1 (0.51) ALDH1A1HPGDHSD17B10CYP3A4AKR1C4
SCHEMBL28704965 0.82 CYP3A4 (0.65) ALDH1A1HPGDHSD17B10CYP3A4AKR1C4
SCHEMBL27750939 0.81 ALDH1A1 (0.49) ALDH1A1HPGDHSD17B10CYP3A4AKR1C4
SCHEMBL8977878 0.80 ALDH1A1 (0.47) ALDH1A1HPGDHSD17B10CYP3A4AKR1C4
SCHEMBL29264039 0.80 ALDH1A1 (0.54) ALDH1A1HPGDHSD17B10KDM4EMEN1
SCHEMBL669840 0.80 HTT (0.50) ALDH1A1HPGDHSD17B10CYP3A4TP53
SCHEMBL10796654 0.79 GABRP (0.47) ALDH1A1GABRPGABRDGABRA1GABRB1
SCHEMBL30810293 0.79 ALDH1A1 (0.76) ALDH1A1HPGDHSD17B10CYP3A4GABRP
SCHEMBL14564097 0.79 ALDH1A1 (0.76) ALDH1A1HPGDHSD17B10CYP3A4GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3148962-B1 PROCESS TO PREPARE 3-METHYL-2-NITROBENZOIC ACID BY AIR OXIDATION FMC AGRO SINGAPORE PTE LTD (SG) 2020-05-13 EP disclosed