Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL29007335 | 0.97 | ACHE (0.44) | ACHEFFAR3NOS1TSHRCYP2C19 | |
| Carbamic Acid SCHEMBL28546467 | 0.97 | ACHE (0.44) | ACHEFFAR3NOS1TSHRCYP2C19 | |
| Acetic Acid SCHEMBL3228026 | 0.83 | FFAR3 (0.50) | FFAR3TSHRCYP2C19ALDH1A1CYP2D6 | |
| Carbamic Acid SCHEMBL29007334 | 0.81 | FFAR3 (0.35) | FFAR3NOS1TSHRCYP2C19ALDH1A1 | |
| Diethyl Sulfide SCHEMBL11503638 | 0.80 | — | — | |
| SCHEMBL17340316 | 0.79 | — | — | |
| Carbamic Acid SCHEMBL27929645 | 0.78 | — | — | |
| Carbamic Acid SCHEMBL21986556 | 0.78 | — | — | |
| Diethyl Sulfide SCHEMBL10511075 | 0.78 | TSHR (0.44) | ACHEFFAR3NOS1TSHRCYP2C19 | |
| SCHEMBL14157228 | 0.77 | TDP1 (0.63) | NOS1TSHRCYP2C19ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3914241-A1 | ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME | Yale University (US) | 2021-12-01 | — | — | EP | disclosed |
| US-20210085796-A1 | ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME | YALE UNIVERSITY | 2021-03-25 | — | — | US | disclosed |
| WO-2020154672-A1 | ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME | YALE UNIVERSITY (US) | 2020-07-30 | — | — | WO | disclosed |
| CN-108484807-B | Preparation method of rigid chain liquid crystal polymer with perylene bisimide (PDI) as side group and photoelectric property | 湘潭大学 | 2020-06-19 | — | — | CN | disclosed |
| EP-3659307-A1 | Anticancer Drugs and Methods of Making and Using Same | Yale University (US) | 2020-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210085796-A1 | ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME | MTHFD1, DHFR, ABCG2 | ACHE 1977/4885FFAR3 3000/4885NOS1 3718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.