SCHEMBL2198711

SCHEMBL2198711

CC(OC(=O)C(N)(CCCCCN)C(=O)OC(C)c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])c1ccc([N+](=O)[O-])cc1[N+](=O)[O-]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
TDP1 Q9NUW8 7/20 0.37
GRM8 O00222 1/20 0.37
GRM4 Q14833 1/20 0.37
SMN1; SMN2 Q16637 4/20 0.37
POLB P06746 3/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 4/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.35
MAPK1 P28482 4/20 0.35
GAA P10253 1/20 0.35
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
GPR35 Q9HC97 1/20 0.34
HIF1A Q16665 1/20 0.34
KAT2B Q92831 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7564174 0.86 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2POLBCYP1A2GAA
SCHEMBL2202119 0.86 ALDH1A1 (0.38) ALDH1A1TDP1SMN1; SMN2POLBLMNA
SCHEMBL2203139 0.84 MMP2 (0.40) ALDH1A1SMN1; SMN2POLBLMNAMAPT
SCHEMBL27736694 0.83 ALDH1A1 (0.43) ALDH1A1TDP1GRM8GRM4SMN1; SMN2
SCHEMBL2197778 0.81 ADRB2 (0.35) ALDH1A1GRM8GRM4SMN1; SMN2LMNA
SCHEMBL2200132 0.80 CYP1A2 (0.45) ALDH1A1TDP1SMN1; SMN2POLBMAPT
SCHEMBL11159565 0.76 ALDH1A1 (0.47) ALDH1A1TDP1GRM8GRM4SMN1; SMN2
SCHEMBL27736702 0.74 ALDH1A1 (0.48) ALDH1A1TDP1GRM8GRM4SMN1; SMN2
SCHEMBL2201163 0.73 ALDH1A1 (0.35) ALDH1A1TDP1POLBLMNAMAPT
SCHEMBL8079837 0.72 KAT2B (0.44) ALDH1A1TDP1SMN1; SMN2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1909142-B1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES (JP) 2015-06-24 EP disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
EP-1909142-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES, INC. (JP) 2008-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 ALDH1A1 1144/4885TDP1 652/4885GRM8 1712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.