SCHEMBL2198752

SCHEMBL2198752

CCC(c1cccc(O)c1N)c1cccc(O)c1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
BCHE P06276 1/20 0.45
TYR P14679 1/20 0.45
ACHE P22303 1/20 0.45
G6PD P11413 1/20 0.42
CASP7 P55210 1/20 0.42
CASP6 P55212 1/20 0.42
HIF1A Q16665 2/20 0.40
KDM4E B2RXH2 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
POLB P06746 1/20 0.40
GABRA1 P14867 3/20 0.39
GABRB2 P47870 2/20 0.39
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HPGD P15428 3/20 0.35
LMNA P02545 3/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28261050 0.91 TSHR (0.48) TSHRBCHETYRACHEG6PD
SCHEMBL19405735 0.87 CASP7 (0.57) TSHRBCHETYRACHEG6PD
SCHEMBL6885162 0.84 TSHR (0.48) TSHRBCHETYRACHEG6PD
SCHEMBL27511455 0.82 TSHR (0.68) TSHRBCHETYRACHEG6PD
SCHEMBL6542924 0.79 CD44 (0.43) TSHRBCHETYRACHECASP7
SCHEMBL29270107 0.79 G6PD (0.56) TSHRBCHETYRACHEG6PD
SCHEMBL29860994 0.79 TSHR (0.68) TSHRBCHETYRACHEHIF1A
SCHEMBL296591 0.79 TSHR (0.68) TSHRBCHETYRACHEHIF1A
SCHEMBL28029041 0.78 BCHE (0.51) TSHRBCHETYRACHEHIF1A
SCHEMBL27518770 0.78 KDM4E (0.43) TSHRBCHETYRACHEG6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1909142-B1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES (JP) 2015-06-24 EP disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
EP-1909142-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES, INC. (JP) 2008-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 TSHR 4306/4885BCHE 4032/4885TYR 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.