Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899229 | 0.83 | CD44 (0.43) | CD44ALDH1A1CYP3A4TSHRPIK3CA | |
| SCHEMBL1602038 | 0.82 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TSHRPIK3CAGPR84 | |
| SCHEMBL8085544 | 0.81 | CYP3A4 (0.52) | CD44ALDH1A1CYP3A4TSHRPIK3CA | |
| SCHEMBL2198759 | 0.81 | MMP2 (0.44) | CD44ALDH1A1CYP3A4TSHRPIK3CA | |
| SCHEMBL6004009 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRPIK3CAGPR84 | |
| SCHEMBL6317155 | 0.79 | CYP3A4 (0.38) | CD44ALDH1A1CYP3A4TSHRPIK3CA | |
| SCHEMBL6317153 | 0.79 | PNMT (0.42) | ALDH1A1CYP3A4TSHRGPR84TAAR1 | |
| SCHEMBL6313117 | 0.79 | GABRA1 (0.40) | ALDH1A1TSHRGPR84BCHETYR | |
| SCHEMBL2198752 | 0.79 | TSHR (0.48) | ALDH1A1CYP3A4TSHRGPR84TDP1 | |
| SCHEMBL1660721 | 0.79 | CD44 (0.40) | CD44ALDH1A1CYP3A4TSHRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149629-B1 | Hydrogenation of aromatic amines using lithium aluminate as the catalyst support | AIR PROD & CHEM (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1149629-A1 | Hydrogenation of aromatic amines using lithium aluminate as the catalyst support | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2001-10-31 | — | — | EP | disclosed |
| US-6184416-B1 | THE USE OF A RHODIUM CATALYST CARRIED ON A LITHIUM ALUMINATE (LIAL5O8) SUPPORT RING HYDROGENATE AROMATIC AMINES; CATALYST SELECTIVITY; REUSE OF THE CATALYST; CAN BE USED WITH ALKALI METAL REACTION PROMOTERS; LOW WATER SOLUBILITY; KINETICS | AIR PRODUCTS AND CHEMICALS, INC. | 2001-02-06 | — | — | US | disclosed |
| US-6140540-A | USING MIXTURE OF COBALT WITH RHODIUM, RUTHENIUM, PALLADIUM AND, OR PLATIMUM | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0630882-B1 | Hydrogenation of aromatic amines to produce their ring hydrogenated counterparts | AIR PROD & CHEM (US) | 1997-11-05 | — | — | EP | disclosed |
| EP-0618188-B1 | Process for the preparation of cyclohexylamines by catalytic hydrogenation of anilines | AIR PROD & CHEM (US) | 1997-09-17 | — | — | EP | disclosed |
| US-5545756-A | RHODIUM HYDROGENATION CATALYST ON SUPPORT | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0630882-A1 | Hydrogenation of aromatic amines to produce their ring hydrogenated counterparts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5360934-A | Aluminum oxide supported rhodium catalyst | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1994-11-01 | — | — | US | disclosed |
| EP-0618188-A2 | Process for the preparation of cyclohexylamines by catalytic hydrogenation of anilines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1994-10-05 | — | — | EP | disclosed |
| EP-0392435-B1 | HYDROGENATION OF AROMATIC AMINES USING RHODIUM ON TITANIA OR ZIRCONIA SUPPORT | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1993-09-29 | — | — | EP | disclosed |
| EP-0335272-B1 | HYDROGENATION OF AROMATIC AMINES TO PRODUCE THEIR RING HYDROGENATED COUNTERPARTS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1993-09-22 | — | — | EP | disclosed |
| US-5026914-A | Catalyst selectivity | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0392435-A1 | Hydrogenation of aromatic amines using rhodium on titania or zirconia support | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-10-17 | — | — | EP | disclosed |
| US-4960941-A | HYDROGENATION CATALYST OF RHODIUM ON TITANIA SUPPORT | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0335272-A2 | Hydrogenation of aromatic amines to produce their ring hydrogenated counterparts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-10-04 | — | — | EP | disclosed |