Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17699256 | 0.66 | THRB (0.39) | APEX1THRBATMKDM4EALDH1A1 | |
| SCHEMBL10378479 | 0.59 | — | — | |
| SCHEMBL31337844 | 0.59 | HCAR2 (0.39) | APEX1THRBATMKDM4EALDH1A1 | |
| SCHEMBL6446355 | 0.59 | HCAR2 (0.39) | APEX1THRBATMKDM4EALDH1A1 | |
| SCHEMBL183861 | 0.59 | HCAR2 (0.39) | APEX1THRBATMKDM4EALDH1A1 | |
| SCHEMBL23135099 | 0.57 | HCAR2 (0.36) | APEX1THRBKDM4EALDH1A1HPGD | |
| SCHEMBL1225040 | 0.57 | HCAR2 (0.38) | APEX1THRBATMKDM4EALDH1A1 | |
| SCHEMBL1225045 | 0.57 | HCAR2 (0.38) | APEX1THRBATMKDM4EALDH1A1 | |
| SCHEMBL22462693 | 0.57 | PKM (0.37) | APEX1THRBATMKDM4EALDH1A1 | |
| SCHEMBL22462692 | 0.57 | PKM (0.37) | APEX1THRBATMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130465-B1 | HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA NV (BE) | 2020-05-13 | — | — | EP | disclosed |