Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAPGEF3 | O95398 | 4/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534850 | 0.87 | CES2 (0.48) | ALDH1A1SMN1; SMN2NPC1HTTRAB9A | |
| SCHEMBL3098687 | 0.82 | MAPT (0.59) | ALDH1A1TSHRHSD17B10MAPTMEN1 | |
| SCHEMBL6619666 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL7144741 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRHSD17B10MAPTMEN1 | |
| Bromide SCHEMBL6280874 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10MAPTMEN1 | |
| Bromide SCHEMBL6545831 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL10392108 | 0.79 | MDM2 (0.47) | ALDH1A1HTTCES2CES1TP53 | |
| SCHEMBL682581 | 0.78 | CES2 (0.53) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1121616 | 0.78 | LMNA (0.49) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7508723 | 0.78 | PLK1 (0.41) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174253-B2 | Compound and pharmaceutical composition containing the same | ALPHALA CO., LTD. (TW) | 2021-11-16 | — | — | US | disclosed |
| US-20200172531-A1 | Novel compound and pharmaceutical composition containing the same | ALPHALA CO., LTD. (TW) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172531-A1 | Novel compound and pharmaceutical composition containing the same | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, F12, ZYX | ALDH1A1 2703/4885TSHR 2518/4885HSD17B10 1928/4885 |
| US-11174253-B2 | Compound and pharmaceutical composition containing the same | F12, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ZYX | ALDH1A1 1878/4885TSHR 2686/4885HSD17B10 2336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.