Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20779328 | 0.82 | KMT2A (0.42) | RAB9ANPC1KMT2APOLBALDH1A1 | |
| SCHEMBL21416769 | 0.76 | NPSR1 (0.43) | RAB9ANPC1KMT2APOLBALDH1A1 | |
| SCHEMBL24137699 | 0.75 | NPC1 (0.42) | RAB9ANPC1KMT2APOLBALDH1A1 | |
| SCHEMBL21417007 | 0.73 | NPC1 (0.42) | RAB9ANPC1KMT2APOLBALDH1A1 | |
| SCHEMBL18844775 | 0.73 | NPC1 (0.46) | RAB9ANPC1KMT2APOLBALDH1A1 | |
| SCHEMBL13885945 | 0.71 | TOP1 (0.42) | KMT2AALDH1A1MEN1GAACYP1A2 | |
| SCHEMBL15627037 | 0.70 | POLB (0.57) | RAB9ANPC1KMT2APOLBALDH1A1 | |
| SCHEMBL23476007 | 0.70 | PRSS1 (0.47) | RAB9ANPC1KMT2APOLBALDH1A1 | |
| SCHEMBL823156 | 0.69 | RAB9A (0.75) | RAB9ANPC1KMT2APOLBMEN1 | |
| SCHEMBL22966294 | 0.68 | MEN1 (0.36) | RAB9ANPC1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227262-B1 | SULFIDE ALKYL AND PYRIDYL REVERSE SULFONAMIDE COMPOUNDS FOR HBV TREATMENT | NOVIRA THERAPEUTICS INC (US) | 2020-05-13 | — | — | EP | disclosed |