Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.60 |
| ▸ | PPARA | Q07869 | 11/20 | 0.60 |
| ▸ | PTGES | O14684 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23605966 | 0.96 | PPARG (0.56) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL21991782 | 0.90 | CTRC (0.59) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL619783 | 0.87 | PPARG (0.59) | PPARGPPARASLC6A9PTPN1 | |
| SCHEMBL21991229 | 0.86 | PPARG (0.48) | PPARGPPARASLC6A9 | |
| SCHEMBL21991735 | 0.86 | PPARG (0.48) | PPARGPPARAPTGESALOX5SLC6A9 | |
| SCHEMBL16571566 | 0.85 | PPARG (0.67) | PPARGPPARASLC6A9PTPN1 | |
| SCHEMBL21991237 | 0.84 | PPARG (0.46) | PPARGPPARAPTGESALOX5SLC6A9 | |
| SCHEMBL1565681 | 0.84 | PPARA (0.57) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL21991252 | 0.83 | PPARG (0.45) | PPARGPPARAALOX5SLC6A9ALDH2 | |
| SCHEMBL21991250 | 0.83 | PPARG (0.45) | PPARGPPARASLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11318111-B2 | CCL5 inhibitors | LAPKO INC (US) | 2022-05-03 | — | — | US | disclosed |
| US-20210196665-A1 | CCL5 Inhibitors | AFECTA PHARMACEUTICALS, INC. (US) | 2021-07-01 | — | — | US | disclosed |
| US-10940132-B2 | CCL5 inhibitors | AFECTA PHARMACEUTICALS, INC. (US) | 2021-03-09 | — | — | US | disclosed |
| US-20200138766-A1 | CCL5 INHIBITORS | LAPKO INC. DBA AFECTA PHARMACEUTICALS | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200138766-A1 | CCL5 INHIBITORS | CCL5, CCL11, CCR5 | PPARG 1583/4885PPARA 806/4885PTGES 127/4885 |
| US-20210196665-A1 | CCL5 Inhibitors | CCL5, CCL11, CCR5 | PPARG 1583/4885PPARA 806/4885PTGES 127/4885 |
| US-10940132-B2 | CCL5 inhibitors | CCL5, CCL11, CCR5 | PPARG 1583/4885PPARA 806/4885PTGES 127/4885 |
| US-11318111-B2 | CCL5 inhibitors | CCL5, CCL11, CCR5 | PPARG 1583/4885PPARA 806/4885PTGES 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.