Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25095261 | 1.00 | ADORA2A (0.49) | ADORA2AADORA2BDRD1DRD5ADORA3 | |
| SCHEMBL20624337 | 1.00 | ADORA2A (0.49) | ADORA2AADORA2BDRD1DRD5ADORA3 | |
| SCHEMBL21992894 | 1.00 | ADORA2A (0.49) | ADORA2AADORA2BDRD1DRD5ADORA3 | |
| SCHEMBL22435235 | 0.77 | ADORA1 (0.50) | ADORA2AADORA3LMNACYP1A2PMP22 | |
| 8-Cyclopentyltheophylline SCHEMBL6742249 | 0.73 | ADORA2A (0.66) | ADORA2AADORA2BADORA3LMNACYP1A2 | |
| SCHEMBL9910656 | 0.72 | XDH (0.42) | ADORA3PMP22CYP3A4MAPK1KMT2A | |
| SCHEMBL3427614 | 0.71 | CDK1 (0.47) | ADORA2ALMNAPMP22CYP3A4MAPK1 | |
| SCHEMBL18521149 | 0.71 | CDK1 (0.40) | ADORA2APMP22CYP3A4MAPK1ADORA1 | |
| 9-Methylguanine SCHEMBL22884 | 0.71 | XDH (0.58) | MEN1TSHRKMT2A | |
| SCHEMBL7449080 | 0.71 | ADORA2A (0.39) | ADORA2AADORA2BADORA3LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814407-B2 | Multiple coupling and oxidation method | ROCHE INNOVATION CENTER COPENHAGEN A/S (CH) | 2023-11-14 | — | — | US | disclosed |
| US-20210179658-A1 | ORTHOGONAL PROTECTING GROUPS FOR THE PREPARATION OF STEREODEFINED PHOSPHOROTHIOATE OLIGONUCLEOTIDES | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2021-06-17 | — | — | US | disclosed |
| US-20200148714-A1 | MULTIPLE COUPLING & OXIDATION METHOD | ROCHE INNOVATION CENTER COPENHAGEN A/S (CH) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179658-A1 | ORTHOGONAL PROTECTING GROUPS FOR THE PREPARATION OF STEREODEFINED PHOSPHOROTHIOATE OLIGONUCLEOTIDES | PCNA, RNGTT, POLL | ADORA2A 1317/4885ADORA2B 1042/4885DRD1 1802/4885 |
| US-11814407-B2 | Multiple coupling and oxidation method | RNGTT, PCNA, TYMP | ADORA2A 1230/4885ADORA2B 1945/4885DRD1 2371/4885 |
| US-20200148714-A1 | MULTIPLE COUPLING & OXIDATION METHOD | POLRMT, POLM, RNGTT | ADORA2A 1245/4885ADORA2B 1934/4885DRD1 2379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.