SCHEMBL21993832

SCHEMBL21993832

CCCCCCCCn1c(=O)c(-c2ccc(/C=C3\SC(=S)N(CC)C3=O)cc2)cc2c1cc(-c1ccc(/C=C3\SC(=S)N(CC)C3=O)cc1)c(=O)n2CCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DNM1 Q05193 1/20 0.48
▸ ALDH1A1 P00352 4/20 0.47
▸ MAOA P21397 1/20 0.47
▸ MAOB P27338 1/20 0.47
▸ PDE4B Q07343 2/20 0.47
▸ MAPT P10636 5/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ LMNA P02545 2/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ IDE P14735 1/20 0.43
▸ ALOX12 P18054 1/20 0.43
▸ TNNI3 P19429 1/20 0.43
▸ TNNT2 P45379 1/20 0.43
▸ TNNC1 P63316 1/20 0.43
▸ MYC P01106 3/20 0.43
▸ MAX P61244 3/20 0.43
▸ MAPK1 P28482 2/20 0.43
▸ KDM4E B2RXH2 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21993650 0.84 TNFRSF1A (0.52) DNM1ALDH1A1MAOAMAOBPDE4B
SCHEMBL21993831 0.76 KDM4E (0.41) ALDH1A1MAPTLMNANPC1MAPK1
SCHEMBL7862697 0.74 NLRP3 (0.64) DNM1ALDH1A1MAOAMAOBPDE4B
SCHEMBL21501972 0.71 MAPT (0.46) ALDH1A1MAPTNPC1KDM4ETHRB
SCHEMBL13727246 0.71 MEN1 (0.68) DNM1ALDH1A1MAOAMAOBPDE4B
SCHEMBL17051283 0.71 MYC (0.76) DNM1ALDH1A1MAOAMAOBPDE4B
SCHEMBL18857854 0.71 MEN1 (0.68) DNM1ALDH1A1MAOAMAOBPDE4B
SCHEMBL13727245 0.71 MEN1 (0.68) DNM1ALDH1A1MAOAMAOBPDE4B
SCHEMBL24129903 0.71 CISD1 (0.67) DNM1ALDH1A1MAOAMAOBPDE4B
SCHEMBL2447131 0.71 CISD1 (0.67) DNM1ALDH1A1MAOAMAOBPDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11075344-B2 Organic device and image sensor SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-07-27 — — US disclosed
US-20200152888-A1 ORGANIC DEVICE AND IMAGE SENSOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-05-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200152888-A1 ORGANIC DEVICE AND IMAGE SENSOR CHRM1, NCS1, OR10J3 DNM1 2295/4885ALDH1A1 254/4885MAOA 940/4885
US-11075344-B2 Organic device and image sensor CHRM1, NCS1, OR10J3 DNM1 2295/4885ALDH1A1 254/4885MAOA 940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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