Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28013975 | 0.80 | CYP19A1 (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL4217666 | 0.76 | RAB9A (0.43) | MAPTALDH1A1KDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL11455497 | 0.75 | CYP19A1 (0.44) | MAPTALDH1A1KDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL31426296 | 0.74 | AR (0.35) | CYP3A4 | |
| SCHEMBL21993945 | 0.73 | TRPA1 (0.40) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6799195 | 0.73 | MAPT (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL28013299 | 0.73 | CYP19A1 (0.47) | MAPTALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL903245 | 0.73 | MAPT (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL22536181 | 0.73 | CYP19A1 (0.47) | MAPTALDH1A1ALOX12CYP19A1ALOX15 | |
| Hydrochloric Acid SCHEMBL10646143 | 0.71 | TDP1 (0.39) | MAPTALDH1A1KDM4ESMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11141402-B2 | Compounds useful in inhibiting human trefoil factor 3 | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2021-10-12 | — | — | US | disclosed |
| US-20200147039-A1 | COMPOUNDS USEFUL IN INHIBITING HUMAN TREFOIL FACTOR 3 | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11141402-B2 | Compounds useful in inhibiting human trefoil factor 3 | ETF1, F3, DNASE1L3 | MAPT 4590/4885ALDH1A1 3051/4885KDM4E 3966/4885 |
| US-20200147039-A1 | COMPOUNDS USEFUL IN INHIBITING HUMAN TREFOIL FACTOR 3 | ETF1, F3, DNASE1L3 | MAPT 4590/4885ALDH1A1 3051/4885KDM4E 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.