Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17964135 | 0.83 | HTT (0.43) | CYP2C9LMNATSHRAPEX1SMN1; SMN2 | |
| SCHEMBL21994706 | 0.80 | PLAU (0.40) | LMNASMN1; SMN2HTTPLAUIDO1 | |
| SCHEMBL3228865 | 0.76 | TSHR (0.41) | CYP2C9LMNATSHRAPEX1SMN1; SMN2 | |
| SCHEMBL17325379 | 0.75 | GRIN2B (0.38) | CYP2C9LMNATSHRAPEX1SMN1; SMN2 | |
| SCHEMBL14921130 | 0.75 | LMNA (0.39) | CYP2C9LMNATSHRAPEX1SMN1; SMN2 | |
| SCHEMBL14920915 | 0.75 | GRIN2B (0.40) | CYP2C9LMNATSHRAPEX1SMN1; SMN2 | |
| SCHEMBL10204664 | 0.74 | LMNA (0.39) | CYP2C9LMNATSHRAPEX1SMN1; SMN2 | |
| SCHEMBL14921080 | 0.73 | LMNA (0.41) | CYP2C9LMNATSHRAPEX1SMN1; SMN2 | |
| SCHEMBL31409993 | 0.72 | CYP2C9 (0.35) | CYP2C9LMNATSHRAPEX1SMN1; SMN2 | |
| SCHEMBL17186974 | 0.71 | PLAU (0.40) | CYP2C9LMNATSHRAPEX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4156936-A1 | ACTIVE COMPOUND COMBINATIONS | Bayer Aktiengesellschaft (DE) | 2023-04-05 | — | — | EP | disclosed |
| WO-2021239766-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-02 | — | — | WO | disclosed |
| EP-3887362-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020109391-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-04 | — | — | WO | disclosed |