Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ATF1 | P18846 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14921072 | 0.83 | GLA (0.52) | LMNAPLAUGLAHPGDSMN1; SMN2 | |
| SCHEMBL10671281 | 0.77 | LMNA (0.41) | LMNAL3MBTL1PLAUHCAR2CCR9 | |
| SCHEMBL14932583 | 0.77 | L3MBTL1 (0.41) | L3MBTL1HPGDTSHRSMN1; SMN2HTT | |
| SCHEMBL17964135 | 0.77 | HTT (0.43) | LMNAL3MBTL1PLAUHPGDTSHR | |
| SCHEMBL21994824 | 0.73 | CYP2C9 (0.37) | LMNAL3MBTL1PLAUTSHRSMN1; SMN2 | |
| SCHEMBL14921130 | 0.73 | LMNA (0.39) | LMNAL3MBTL1PLAUHPGDTRPM8 | |
| SCHEMBL23119566 | 0.71 | ASPH (0.45) | HCAR2CCR9DHODHATF1NFKB1 | |
| SCHEMBL27176554 | 0.70 | ALK (0.39) | LMNAL3MBTL1GLAHPGDCCR9 | |
| SCHEMBL30707926 | 0.70 | ALK (0.39) | LMNAL3MBTL1GLAHPGDCCR9 | |
| SCHEMBL31410031 | 0.70 | PLAU (0.42) | LMNAL3MBTL1PLAUTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9301526-B2 | Compounds with nematicidal activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-05 | — | — | US | disclosed |
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| EP-2773215-A2 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | Bayer Intellectual Property GmbH (DE) | 2014-09-10 | — | — | EP | disclosed |
| EP-2773203-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | Bayer Intellectual Property GmbH (DE) | 2014-09-10 | — | — | EP | disclosed |
| US-20140249149-A1 | Compounds with Nematicidal Activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| EP-2606728-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-06-26 | — | — | EP | disclosed |
| EP-2606727-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-06-26 | — | — | EP | disclosed |
| WO-2013064460-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013064461-A2 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | ACHE, TUBA3C, NAAA | LMNA 1026/4885L3MBTL1 894/4885PLAU 3610/4885 |
| US-20140249149-A1 | Compounds with Nematicidal Activity | ACHE, NAAA, TUBA3C | LMNA 1201/4885L3MBTL1 1501/4885PLAU 3521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.