Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20271847 | 0.82 | ALDH1A1 (0.46) | LMNAL3MBTL1SMN1; SMN2HTTPLAU | |
| SCHEMBL14920915 | 0.81 | GRIN2B (0.40) | GRIN2BLMNAL3MBTL1CYP2C9TSHR | |
| SCHEMBL14921130 | 0.81 | LMNA (0.39) | GRIN2BLMNAL3MBTL1CYP2C9TSHR | |
| SCHEMBL17964135 | 0.78 | HTT (0.43) | GRIN2BLMNAL3MBTL1CYP2C9TSHR | |
| SCHEMBL20271127 | 0.76 | HTT (0.36) | LMNASMN1; SMN2HTT | |
| SCHEMBL21994824 | 0.75 | CYP2C9 (0.37) | GRIN2BLMNAL3MBTL1CYP2C9TSHR | |
| SCHEMBL17315783 | 0.72 | LMNA (0.41) | GRIN2BLMNAL3MBTL1CYP2C9TSHR | |
| SCHEMBL3228865 | 0.71 | TSHR (0.41) | LMNAL3MBTL1CYP2C9TSHRAPEX1 | |
| SCHEMBL13894474 | 0.71 | LMNA (0.37) | LMNAL3MBTL1CYP2C9TSHRAPEX1 | |
| SCHEMBL10204664 | 0.70 | LMNA (0.39) | LMNAL3MBTL1CYP2C9TSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015187845-A1 | DIFLUOROETHYLPYRIDINE DERIVATIVES AS NR2B NMDA RECEPTOR ANTAGONISTS | RUGEN HOLDINGS (CAYMAN) LIMITED (KY) | 2015-12-10 | — | — | WO | disclosed |