Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 7/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514065 | 1.00 | TRPV4 (0.43) | TRPV4FFAR4ALDH1A1LMNAPKM | |
| SCHEMBL17376428 | 0.80 | KAT6A (0.38) | LMNAKMT2AGLAHPGD | |
| SCHEMBL21995249 | 0.79 | MEP1B (0.42) | ALDH1A1LMNAKMT2AGLAGAA | |
| SCHEMBL30773057 | 0.79 | MEP1B (0.42) | ALDH1A1LMNAKMT2AGLAGAA | |
| SCHEMBL29250332 | 0.78 | SLC22A12 (0.52) | ALDH1A1KMT2ASLC22A12 | |
| SCHEMBL22056787 | 0.76 | GABRA1 (0.37) | TRPV4ALDH1A1PKMGLAGAA | |
| SCHEMBL22057011 | 0.76 | GLA (0.36) | ALDH1A1LMNAKMT2AGLACYP2C19 | |
| SCHEMBL12879058 | 0.75 | PIK3CD (0.44) | TRPV4FFAR4KMT2ACYP2C19ABCB11 | |
| SCHEMBL31514048 | 0.74 | MCOLN3 (0.48) | TRPV4ALDH1A1LMNAPKMHTT | |
| SCHEMBL21994820 | 0.74 | MCOLN3 (0.48) | TRPV4ALDH1A1LMNAPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509462-B2 | 3-(phenylsulfonyl)-[1,2,3]triazolo[1,5A]quinazolin-5(4H)-one derivatives | BioVersys AG (CH) | 2025-12-30 | — | — | US | disclosed |
| EP-3887375-B1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | BioVersys AG (CH) | 2024-11-20 | — | — | EP | disclosed |
| US-20220024928-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | BioVersys AG (CH) | 2022-01-27 | — | — | US | disclosed |
| US-20220024928-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | BioVersys AG (CH) | 2022-01-27 | — | — | US | disclosed |
| EP-3887375-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | Bioversys AG (CH) | 2021-10-06 | — | — | EP | disclosed |
| CN-113195493-A | 3- (benzenesulfonyl) - [1,2,3] triazolo [1,5a ] quinazolin-5 (4H) -one derivatives | 生物验证系统股份公司 | 2021-07-30 | — | — | CN | disclosed |
| WO-2020109350-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | BioVersys AG (CH) | 2020-06-04 | — | — | WO | disclosed |
| WO-2020109350-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | BioVersys AG (CH) | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024928-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | OR10J3, ORC3, CBR3 | TRPV4 1487/4885FFAR4 2997/4885ALDH1A1 1547/4885 |
| US-12509462-B2 | 3-(phenylsulfonyl)-[1,2,3]triazolo[1,5A]quinazolin-5(4H)-one derivatives | CUTA, OR10J3, CCR10 | TRPV4 2399/4885FFAR4 2689/4885ALDH1A1 1420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.