SCHEMBL21995535

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9507636	0.81	NPC1 (0.47)	KDM4EMEN1GAAKMT2AHSD17B10
	SCHEMBL9224618	0.81	NPC1 (0.47)	KDM4EMEN1GAAKMT2AHSD17B10
	SCHEMBL8970762	0.81	NPC1 (0.47)	KDM4EMEN1GAAKMT2AHSD17B10
	SCHEMBL26449578	0.79	KDM4E (0.57)	KDM4EMEN1GAAKMT2AHSD17B10
	SCHEMBL9510040	0.78	ALDH1A1 (0.50)	KDM4EHSD17B10TSHRHTTL3MBTL1
	SCHEMBL9506166	0.78	ALDH1A1 (0.50)	KDM4EHSD17B10TSHRHTTL3MBTL1
	SCHEMBL9506149	0.78	ALDH1A1 (0.50)	KDM4EHSD17B10TSHRHTTL3MBTL1
	SCHEMBL9507596	0.78	ALDH1A1 (0.50)	KDM4EHSD17B10TSHRHTTL3MBTL1
	SCHEMBL9506138	0.78	ALDH1A1 (0.50)	KDM4EHSD17B10TSHRHTTL3MBTL1
	SCHEMBL9506321	0.78	ALDH1A1 (0.50)	KDM4EHSD17B10TSHRHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.