SCHEMBL2199626

SCHEMBL2199626

[O]c1ccc2ccccc2c1-c1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.50
TYMP P19971 1/20 0.45
ALDH1A1 P00352 2/20 0.44
CYP2A6 P11509 1/20 0.44
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
WDR5 P61964 1/20 0.42
DHFR P00374 1/20 0.42
PTPN1 P18031 1/20 0.42
CES1 P23141 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALPL P05186 1/20 0.42
GAA P10253 1/20 0.42
GPR84 Q9NQS5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714975 0.84 ALDH1A1 (0.55) DNMT1ALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL29410608 0.78 DNMT1 (0.59) DNMT1TYMPALDH1A1CYP2A6TSHR
SCHEMBL196007 0.78 DNMT1 (0.59) DNMT1TYMPALDH1A1CYP2A6TSHR
SCHEMBL29787010 0.78 DNMT1 (0.59) DNMT1TYMPALDH1A1CYP2A6TSHR
SCHEMBL29407412 0.77 ALDH1A1 (0.50) DNMT1TYMPALDH1A1CYP2A6TSHR
SCHEMBL702934 0.77 ALDH1A1 (0.50) DNMT1TYMPALDH1A1CYP2A6TSHR
SCHEMBL30122801 0.77 DNMT1 (0.47) DNMT1TYMPALDH1A1CYP2A6TSHR
SCHEMBL31307687 0.77 DNMT1 (0.57) DNMT1TYMPALDH1A1CYP2A6TSHR
SCHEMBL29810649 0.77 DNMT1 (0.57) DNMT1TYMPALDH1A1CYP2A6TSHR
SCHEMBL30944688 0.77 DNMT1 (0.47) DNMT1TYMPALDH1A1CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112457342-A Method for synthesizing alkenyl phosphate derivative 辽宁师范大学 2021-03-09 CN claimed
EP-0241235-B1 PROCESS FOR THE PREPARATION OF HOMOALLYL ALCOHOLS ICI AUSTRALIA LIMITED (AU) 1991-02-27 EP claimed
US-20240191067-A1 ETHYLENE-alpha-OLEFIN COPOLYMER, THERMOPLASTIC RESIN COMPOSITION, FILM, AND LAMINATE MITSUI CHEMICALS, INC. (JP) 2024-06-13 US disclosed
US-20240191068-A1 ETHYLENE RESIN COMPOSITION AND SHAPED ARTICLE MITSUI CHEMICALS, INC. (JP) 2024-06-13 US disclosed
US-20240191011-A1 ETHYLENE-alpha-OLEFIN COPOLYMER, THERMOPLASTIC RESIN COMPOSITION, AND FILM MITSUI CHEMICALS, INC. (JP) 2024-06-13 US disclosed
EP-4317215-A1 ETHYLENE RESIN COMPOSITION AND MOLDED BODY Mitsui Chemicals, Inc. (JP) 2024-02-07 EP disclosed
EP-4316834-A1 ETHYLENE-a-OLEFIN COPOLYMER, THERMOPLASTIC RESIN COMPOSITION, AND FILM Mitsui Chemicals, Inc. (JP) 2024-02-07 EP disclosed
EP-4316833-A1 ETHYLENE-a-OLEFIN COPOLYMER, THERMOPLASTIC RESIN COMPOSITION, FILM, AND LAMINATE Mitsui Chemicals, Inc. (JP) 2024-02-07 EP disclosed
WO-2023101004-A1 OLEFIN RESIN, METHOD FOR MANUFACTURING SAME, AND APPLICATION FOR SAME 三井化学株式会社 2023-06-08 WO disclosed
WO-2022210843-A1 ETHYLENE-α-OLEFIN COPOLYMER, THERMOPLASTIC RESIN COMPOSITION, FILM, AND LAMINATE 三井化学株式会社 2022-10-06 WO disclosed
CN-114174246-A Oligomerization process with gaseous headspace recycle IFP 新能源公司 2022-03-11 CN disclosed
US-20070170422-A1 Devices containing chiroptical switching materials and methods of making and using the same NORTH CAROLINA STATE UNIVERSITY 2007-07-26 US disclosed
US-6867161-B1 Titanium catalyst and organotitanium reacting reagent, production thereof, and reaction thereby NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-03-15 US disclosed
US-6479687-B2 REACTING ACETYLENE WITH PHOSPHOROUS ACID COMPOUND IN PRESENCE OF A PALLADIUM CATALYST BASF AKTIENGESELLSCHAFT (DE) 2002-11-12 US disclosed
US-20020004607-A1 Preparation of vinylphosphonic acid compounds HENKELMANN JOCHEM (DE) 2002-01-10 US disclosed
US-6153786-A Method for producing 2-alkynoic acid esters BASF AKTIENGESELLSCHAFT (DE) 2000-11-28 US disclosed
EP-0820809-A1 TITANIUM CATALYST, ORGANOTITANIUM REACTION REAGENT, PROCESSES FOR PRODUCING THESE, AND METHOD OF REACTION USING THESE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1998-01-28 EP disclosed
EP-0241235-B1 PROCESS FOR THE PREPARATION OF HOMOALLYL ALCOHOLS ICI AUSTRALIA LIMITED (AU) 1991-02-27 EP disclosed
US-4933511-A ORGANOMETALLIC CATALYSTS ICI AUSTRALIA LIMITED (AU) 1990-06-12 US disclosed
EP-0241235-A2 Process for the preparation of homoallyl alcohols ICI AUSTRALIA LIMITED (AU) 1987-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070170422-A1 Devices containing chiroptical switching materials and methods of making and using the same PLEC, NCS1, PIEZO1 DNMT1 1492/4885TYMP 2431/4885ALDH1A1 4260/4885
US-20020004607-A1 Preparation of vinylphosphonic acid compounds ACSL6, ACSL1, ACOX1 DNMT1 3122/4885TYMP 513/4885ALDH1A1 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.