Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12330849 | 1.00 | MAPT (0.46) | MAPTALDH1A1L3MBTL1CYP1A2KDM4E | |
| SCHEMBL14132570 | 1.00 | MAPT (0.46) | MAPTALDH1A1L3MBTL1CYP1A2KDM4E | |
| SCHEMBL21998530 | 1.00 | MAPT (0.46) | MAPTALDH1A1L3MBTL1CYP1A2KDM4E | |
| SCHEMBL13515151 | 1.00 | MAPT (0.46) | MAPTALDH1A1L3MBTL1CYP1A2KDM4E | |
| SCHEMBL13515173 | 1.00 | MAPT (0.46) | MAPTALDH1A1L3MBTL1CYP1A2KDM4E | |
| SCHEMBL23471561 | 0.98 | MAPT (0.45) | MAPTALDH1A1L3MBTL1CYP1A2KDM4E | |
| SCHEMBL13808676 | 0.98 | MAPT (0.43) | MAPTALDH1A1L3MBTL1CYP1A2KDM4E | |
| SCHEMBL15858556 | 0.96 | ALDH1A1 (0.46) | MAPTALDH1A1L3MBTL1CYP1A2KDM4E | |
| SCHEMBL15858549 | 0.96 | ALDH1A1 (0.46) | MAPTALDH1A1L3MBTL1CYP1A2KDM4E | |
| SCHEMBL13515162 | 0.93 | ALDH1A1 (0.52) | MAPTALDH1A1L3MBTL1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048923-A1 | LUMINOGENS FOR BIOLOGICAL APPLICATIONS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-02-17 | — | — | US | disclosed |
| US-11186586-B2 | Luminogens for biological applications | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2021-11-30 | — | — | US | disclosed |
| US-20200147078-A1 | THERANOSTIC AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048923-A1 | LUMINOGENS FOR BIOLOGICAL APPLICATIONS | BTD, TPD52L2, TTPA | MAPT 416/4885ALDH1A1 1770/4885L3MBTL1 66/4885 |
| US-11186586-B2 | Luminogens for biological applications | BTD, LTA, TPD52L2 | MAPT 576/4885ALDH1A1 2344/4885L3MBTL1 68/4885 |
| US-20200147078-A1 | THERANOSTIC AGENTS | FAP, MKI67, PAIP1 | MAPT 2200/4885ALDH1A1 1066/4885L3MBTL1 1108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.