SCHEMBL21999232

SCHEMBL21999232

CC(Cc1ccccc1)C(O)S

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.62
CYP2D6 P10635 1/20 0.57
TAAR1 Q96RJ0 4/20 0.50
SIGMAR1 Q99720 4/20 0.50
SLC6A2 P23975 2/20 0.50
MAOA P21397 1/20 0.50
SLC6A4 P31645 1/20 0.50
SLC6A3 Q01959 1/20 0.50
CYP2A6 P11509 1/20 0.50
ADORA2A P29274 1/20 0.50
ADORA1 P30542 1/20 0.50
ACE P12821 3/20 0.47
SLC18A2 Q05940 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
MME P08473 1/20 0.44
CPA1 P15085 1/20 0.44
ACE2 Q9BYF1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21852752 0.84 TRPA1 (0.69) TRPA1CYP2D6TAAR1SIGMAR1SLC6A2
SCHEMBL234669 0.84 TRPA1 (0.69) TRPA1CYP2D6TAAR1SIGMAR1SLC6A2
SCHEMBL19725385 0.84 TRPA1 (0.69) TRPA1CYP2D6TAAR1SIGMAR1SLC6A2
SCHEMBL4951816 0.82 TRPA1 (0.67) TRPA1CYP2D6TAAR1SIGMAR1SLC6A2
SCHEMBL30934 0.81 TRPA1 (0.77) TRPA1CYP2D6TAAR1SIGMAR1SLC6A2
SCHEMBL1140503 0.79 TRPA1 (0.74) TRPA1CYP2D6TAAR1SIGMAR1SLC6A2
Water SCHEMBL3896311 0.79 TRPA1 (0.74) TRPA1CYP2D6TAAR1SIGMAR1SLC6A2
SCHEMBL3075876 0.78 TRPA1 (0.62) TRPA1CYP2D6TAAR1SIGMAR1SLC6A2
SCHEMBL1396351 0.78 CYP2D6 (0.69) TRPA1CYP2D6TAAR1SIGMAR1SLC6A2
Alcohol SCHEMBL6562414 0.77 TRPA1 (0.79) TRPA1CYP2D6TAAR1SIGMAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200148613-A1 METHODS OF MAKING MODIFIED ALCOHOL CONTAINING PRODUCTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2020-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200148613-A1 METHODS OF MAKING MODIFIED ALCOHOL CONTAINING PRODUCTS ADH1C, ADH1A, ADH5 TRPA1 2440/4885CYP2D6 1787/4885TAAR1 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.