Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PTPRF | P10586 | 2/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21999347 | 0.93 | ALOX5 (0.40) | ALOX5PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL21999481 | 0.92 | ALOX5 (0.42) | ALOX5PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL21999592 | 0.92 | ALOX5 (0.42) | ALOX5PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL25980374 | 0.91 | ALOX5 (0.37) | ALOX5PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL24255669 | 0.91 | ALOX5 (0.37) | ALOX5PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL21999319 | 0.91 | PLA2G2A (0.37) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL22000218 | 0.89 | PLA2G2A (0.35) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL22000216 | 0.89 | PLA2G2A (0.38) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL24899588 | 0.89 | MAPT (0.35) | ALOX5MAPTPOLBLMNATSHR | |
| SCHEMBL26779114 | 0.89 | MAPT (0.36) | ALOX5PIM1CSNK2A2CSNK2BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200152883-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200152883-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, TRDMT1, ESD | ALOX5 1482/4885PIM1 2050/4885CSNK2A2 4560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.