Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 10/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111202 | 0.79 | AKR1C4 (0.54) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| Hydrochloric Acid SCHEMBL2512939 | 0.77 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL5878784 | 0.77 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL28392002 | 0.77 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL1301827 | 0.77 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL7539140 | 0.74 | CA12 (0.35) | CA1CA2TSHRSMN1; SMN2TRPV4 | |
| SCHEMBL1546965 | 0.74 | TRPV4 (0.43) | ACLYTSHRSMN1; SMN2TRPV4 | |
| SCHEMBL184213 | 0.74 | CA1 (0.68) | ACLYCA1CA2AKR1C4AKR1C3 | |
| SCHEMBL5704866 | 0.73 | ALDH1A1 (0.50) | ACLYCA1CA2TSHRF2 | |
| Urea SCHEMBL29192961 | 0.73 | AKR1C4 (0.48) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200148634-A1 | ACLY INHIBITORS AND USES THEREOF | Nimbus Artemis, Inc. | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148634-A1 | ACLY INHIBITORS AND USES THEREOF | ACLY, ATP5ME, ATP5MG | ACLY 1/4885CA1 1763/4885CA2 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.