Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360075 | 0.83 | FOLH1 (0.44) | FOLH1NAALAD2MAPTGGT1RIMKLA | |
| SCHEMBL8472248 | 0.81 | FOLH1 (0.52) | TGFBR1FOLH1NAALAD2MAPTRIMKLA | |
| SCHEMBL8472243 | 0.81 | FOLH1 (0.52) | TGFBR1FOLH1NAALAD2MAPTRIMKLA | |
| SCHEMBL18538622 | 0.80 | FPR2 (0.47) | FOLH1NAALAD2MAPTGGT1RIMKLA | |
| SCHEMBL2742767 | 0.80 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL19788058 | 0.80 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18756213 | 0.78 | EPHX1 (0.33) | — | |
| SCHEMBL31690474 | 0.78 | TGFBR1 (0.52) | TGFBR1FOLH1NAALAD2MAPTRIMKLA | |
| Hydrochloric Acid SCHEMBL18725668 | 0.76 | MEN1 (0.34) | — | |
| SCHEMBL880551 | 0.75 | GGT1 (0.58) | TGFBR1FOLH1GGT1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654815-B2 | Urea compound and preparation method and application thereof | SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) | 2020-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654815-B2 | Urea compound and preparation method and application thereof | PDCD1, CD274, PDCD10 | TGFBR1 1440/4885FOLH1 4126/4885NAALAD2 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.