Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 4/20 | 0.35 |
| ▸ | NAAA | Q02083 | 3/20 | 0.35 |
| ▸ | GLB1 | P16278 | 1/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19914951 | 1.00 | ALDH1A1 (0.38) | ALDH1A1USP2ALOX15TDP1POLB | |
| SCHEMBL22002723 | 1.00 | ALDH1A1 (0.38) | ALDH1A1USP2ALOX15TDP1POLB | |
| SCHEMBL16206614 | 0.99 | ALDH1A1 (0.36) | ALDH1A1USP2ALOX15TDP1POLB | |
| SCHEMBL15526611 | 0.93 | PRKCA (0.34) | ALDH1A1USP2ALOX15TDP1POLB | |
| SCHEMBL16206615 | 0.89 | NAAA (0.37) | ALDH1A1USP2L3MBTL1ALOX5TBXA2R | |
| SCHEMBL2793920 | 0.85 | PTGER2 (0.35) | POLBALOX5TBXA2RPTGFRPTGER2 | |
| SCHEMBL6916806 | 0.85 | PTGER2 (0.35) | POLBALOX5TBXA2RPTGFRPTGER2 | |
| SCHEMBL15527693 | 0.84 | TSHR (0.33) | ALDH1A1ALOX5TBXA2RPTGFRPTGER2 | |
| SCHEMBL15527893 | 0.82 | PTGER2 (0.33) | ALDH1A1POLBL3MBTL1PTGER2TSHR | |
| SCHEMBL15527745 | 0.82 | PTGER2 (0.39) | ALDH1A1POLBL3MBTL1PTGER2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654788-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid | L'OREAL (FR) | 2020-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654788-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid | HSD17B12, FASN, AKR1C3 | ALDH1A1 39/4885USP2 2385/4885ALOX15 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.