Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299924 | 1.00 | HIF1A (1.00) | — | |
| SCHEMBL577429 | 1.00 | HIF1A (1.00) | — | |
| SCHEMBL8199316 | 1.00 | HIF1A (1.00) | — | |
| SCHEMBL22003 | 1.00 | HIF1A (1.00) | — | |
| SCHEMBL7052601 | 1.00 | HIF1A (1.00) | — | |
| SCHEMBL5033222 | 1.00 | HIF1A (1.00) | — | |
| SCHEMBL2373879 | 1.00 | HIF1A (1.00) | — | |
| Piperazine SCHEMBL734764 | 1.00 | HIF1A (1.00) | — | |
| SCHEMBL3999265 | 1.00 | HIF1A (1.00) | — | |
| SCHEMBL576335 | 1.00 | HIF1A (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971985-A1 | REACTIVE AZO DYES HAVING A PERMANENT QUATERNARY AMMONIUM GROUP AND A FIBER-REACTIVE GROUP | DyStar L.P. (US) | 2000-01-19 | — | — | EP | claimed |
| US-5932708-A | DYEING COTTON, CELLULOSE, POLYAMIDE, WOOL; HIGH COLOR INTENSITY, COLORFASTNESS | DYSTAR, L.P. (US) | 1999-08-03 | — | — | US | claimed |
| WO-1998042784-A1 | REACTIVE AZO DYES HAVING A PERMANENT QUATERNARY AMMONIUM GROUP AND A FIBER-REACTIVE GROUP | DYSTAR L.P. (US) | 1998-10-01 | — | — | WO | claimed |
| EP-0971985-A1 | REACTIVE AZO DYES HAVING A PERMANENT QUATERNARY AMMONIUM GROUP AND A FIBER-REACTIVE GROUP | DyStar L.P. (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5932708-A | DYEING COTTON, CELLULOSE, POLYAMIDE, WOOL; HIGH COLOR INTENSITY, COLORFASTNESS | DYSTAR, L.P. (US) | 1999-08-03 | — | — | US | disclosed |
| WO-1998042784-A1 | REACTIVE AZO DYES HAVING A PERMANENT QUATERNARY AMMONIUM GROUP AND A FIBER-REACTIVE GROUP | DYSTAR L.P. (US) | 1998-10-01 | — | — | WO | disclosed |