SCHEMBL22004480

SCHEMBL22004480

Fc1ccc(OCc2ccc(C3=CCC(c4ccccc4)C=C3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.42
APP P05067 1/20 0.42
NR4A2 P43354 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 1/20 0.40
RECQL P46063 1/20 0.40
S1PR5 Q9H228 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GPR34 Q9UPC5 1/20 0.39
KDM1A O60341 1/20 0.39
BCL2L1 Q07817 1/20 0.38
MCL1 Q07820 1/20 0.38
AR P10275 1/20 0.38
LMNA P02545 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15079159 0.79 MAOA (0.36) MAOBKDM1A
SCHEMBL22004444 0.76 TRPA1 (0.37) ALDH1A1KDM1A
SCHEMBL28675583 0.75 RECQL (0.31) MAOBRECQLKDM1A
SCHEMBL21993643 0.73 GSTP1 (0.63) MAOBAPPNR4A2MEN1KMT2A
SCHEMBL6927496 0.70 MAOB (0.66) MAOBAPPNR4A2MEN1KMT2A
SCHEMBL4337813 0.70 MEN1 (0.68) MAOBAPPNR4A2MEN1KMT2A
SCHEMBL2718613 0.69 TDP1 (0.45) MEN1KMT2AALDH1A1LMNA
SCHEMBL27550091 0.68 MAOB (0.80) MAOBAPPNR4A2NPC1RAB9A
SCHEMBL19797512 0.68 GPR88 (0.31) MAOBALDH1A1KDM1A
SCHEMBL27854180 0.68 MEN1 (0.57) MAOBAPPNR4A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3653575-A1 SURFACE-MODIFIED INORGANIC NITRIDE, COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, DEVICE PROVIDED WITH THERMALLY CONDUCTIVE LAYER FUJIFILM Corporation (JP) 2020-05-20 EP disclosed