SCHEMBL2200522

SCHEMBL2200522

Nc1ccccc1C(c1ccccc1N)(c1ccccc1N)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.45
CYP3A4 P08684 3/20 0.45
ALOX15 P16050 2/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
ALDH1A1 P00352 5/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 2/20 0.37
POLB P06746 2/20 0.37
TSHR P16473 3/20 0.36
KDM4E B2RXH2 3/20 0.36
GAA P10253 3/20 0.36
MEN1 O00255 3/20 0.35
MAPT P10636 3/20 0.35
KMT2A Q03164 3/20 0.35
NPSR1 Q6W5P4 2/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2800809 0.82 SMN1; SMN2 (0.43) SMN1; SMN2CYP3A4ALOX15CASP1CASP7
SCHEMBL3871150 0.82 SMN1; SMN2 (0.43) SMN1; SMN2CYP3A4ALOX15CASP1CASP7
SCHEMBL29380196 0.82 SMN1; SMN2 (0.43) SMN1; SMN2CYP3A4ALOX15CASP1CASP7
SCHEMBL2729599 0.82 SMN1; SMN2 (0.43) SMN1; SMN2CYP3A4ALOX15CASP1CASP7
SCHEMBL70554 0.81 ALDH1A1 (0.48) SMN1; SMN2CYP3A4ALOX15CASP1CASP7
SCHEMBL29882203 0.81 ALDH1A1 (0.48) SMN1; SMN2CYP3A4ALOX15CASP1CASP7
SCHEMBL8994564 0.81 ALDH1A1 (0.48) SMN1; SMN2CYP3A4ALOX15CASP1CASP7
Hydrochloric Acid SCHEMBL4371044 0.79 TDP1 (0.52) SMN1; SMN2CYP3A4ALOX15CASP1CASP7
Hydrogen Sulfide SCHEMBL11147516 0.79 POLB (0.46) SMN1; SMN2CYP3A4ALOX15CASP1CASP7
Hydrochloric Acid SCHEMBL1768867 0.79 TDP1 (0.52) SMN1; SMN2CYP3A4ALOX15CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1909142-B1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES (JP) 2015-06-24 EP disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
EP-1909142-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES, INC. (JP) 2008-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 SMN1; SMN2 3418/4885CYP3A4 4337/4885ALOX15 919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.