SCHEMBL2800809

SCHEMBL2800809

Nc1ccccc1C(c1ccccc1N)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.43
ALOX15 P16050 2/20 0.43
CYP3A4 P08684 2/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
ALDH1A1 P00352 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
POLB P06746 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
TSHR P16473 2/20 0.35
MEN1 O00255 3/20 0.34
MAPT P10636 3/20 0.34
KMT2A Q03164 3/20 0.34
KDM4E B2RXH2 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
GAA P10253 2/20 0.33
IDO1 P14902 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29380196 1.00 SMN1; SMN2 (0.43) SMN1; SMN2ALOX15CYP3A4CASP1CASP7
SCHEMBL16610456 0.87 ALDH1A1 (0.41) SMN1; SMN2ALOX15CYP3A4CASP1CASP7
SCHEMBL2200522 0.82 SMN1; SMN2 (0.45) SMN1; SMN2ALOX15CYP3A4CASP1CASP7
SCHEMBL8655007 0.81 CD44 (0.39) SMN1; SMN2ALOX15CYP3A4CASP1CASP7
SCHEMBL3871150 0.80 SMN1; SMN2 (0.43) SMN1; SMN2ALOX15CYP3A4CASP1CASP7
SCHEMBL2729599 0.80 SMN1; SMN2 (0.43) SMN1; SMN2ALOX15CYP3A4CASP1CASP7
SCHEMBL8994564 0.79 ALDH1A1 (0.48) SMN1; SMN2ALOX15CYP3A4CASP1CASP7
SCHEMBL70554 0.79 ALDH1A1 (0.48) SMN1; SMN2ALOX15CYP3A4CASP1CASP7
SCHEMBL29882203 0.79 ALDH1A1 (0.48) SMN1; SMN2ALOX15CYP3A4CASP1CASP7
SCHEMBL6757407 0.78 MMP2 (0.39) SMN1; SMN2ALOX15CYP3A4CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055088-A1 COMPOSITION AND METHOD FOR MANUFACTURING RESINS Cambium Biomaterials, Inc. (US) 2022-09-14 EP claimed
EP-3924090-A1 AROMATIC CO-POLYIMIDE GAS SEPARATION MEMBRANES DERIVED FROM 6FDA-6FPDA-TYPE HOMO-POLYIMIDES Saudi Arabian Oil Company (SA) 2021-12-22 EP claimed
WO-2020215025-A1 EXTREME HIGH TEMPERATURE STABLE ADHESIVES AND COATINGS DESIGNER MOLECULES, INC (US) 2020-10-22 WO claimed
US-10428181-B2 Porous cross-linked partially aliphatic polyimide networks OHIO AEROSPACE INSTITUTE (US) 2019-10-01 US claimed
US-20070092743-A1 Liquid crystal display SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-04-26 US claimed
EP-0390992-B1 Aromatic polyimide double layered hollow filamentary membrane and process for producing same UBE INDUSTRIES (JP) 1994-06-01 EP claimed
US-5141642-A Separators for reverse osmosis, ultrafiltration, dehydration, heat and chemical resistance, strength, gas permeability UBE INDUSTRIES, LTD. (JP) 1992-08-25 US claimed
EP-0390992-A1 Aromatic polyimide double layered hollow filamentary membrane and process for producing same UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP claimed
US-12319814-B2 Polyamideimide resin, resin composition, and semiconductor device RESONAC CORPORATION (JP) 2025-06-03 US disclosed
EP-4026867-B1 POLYAMIDEIMIDE RESIN, RESIN COMPOSITION, AND SEMICONDUCTOR DEVICE RESONAC CORP (JP) 2023-12-06 EP disclosed
US-11767412-B2 Manufacturing process for dark-color polymer composite films GLOBAL GRAPHENE GROUP, INC. (US) 2023-09-26 US disclosed
CN-116113884-A Method for producing cured product, method for producing laminate, and method for producing electronic device 富士胶片株式会社 2023-05-12 CN disclosed
US-20220332947-A1 POLYAMIDEIMIDE RESIN, RESIN COMPOSITION, AND SEMICONDUCTOR DEVICE RESONAC CORPORATION (JP) 2022-10-20 US disclosed
EP-4055088-A1 COMPOSITION AND METHOD FOR MANUFACTURING RESINS Cambium Biomaterials, Inc. (US) 2022-09-14 EP disclosed
EP-0385305-A1 Polyamide-imide polymers having fluorine-containing linking groups HOECHST CELANESE CORPORATION (US) 1990-09-05 EP disclosed
US-4954610-A SOLVENT, HEAT, OXIDATION, AND CHEMICAL RESISTANCE HOECHST CELANESE CORP. (US) 1990-09-04 US disclosed
US-4929405-A Ultrathin polyimide polymer flims and their preparation HOECHST CELANESE CORP. (US) 1990-05-29 US disclosed
US-4760126-A Fluorine-containing polyamide-acid derivative and polyimide HITACHI, LTD. (JP) 1988-07-26 US disclosed
EP-0142149-A2 Use of fluorine containing polyimides for aligning layers of liquid crystal display devices. HITACHI, LTD. (JP) 1985-05-22 EP disclosed
US-4370501-A Synthesis of bis(aminophenyl) compounds HUGHES AIRCRAFT COMPANY (US) 1983-01-25 US disclosed