Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1815976 | 0.93 | CYP3A4 (0.49) | CYP3A4SMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL1818269 | 0.90 | AHR (0.43) | SMN1; SMN2MAPTTDP1L3MBTL1FDPS | |
| SCHEMBL28370253 | 0.90 | AHR (0.43) | SMN1; SMN2MAPTTDP1L3MBTL1FDPS | |
| SCHEMBL28673732 | 0.87 | APP (0.46) | CYP3A4SMN1; SMN2MAPTL3MBTL1APP | |
| SCHEMBL15948906 | 0.87 | LMNA (0.44) | SMN1; SMN2MAPTL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL25954061 | 0.84 | ELANE (0.46) | SMN1; SMN2MAPTTDP1APPALDH1A1 | |
| SCHEMBL164160 | 0.84 | ELANE (0.46) | SMN1; SMN2MAPTTDP1APPALDH1A1 | |
| SCHEMBL22113474 | 0.83 | ALDH1A1 (0.47) | SMN1; SMN2MAPTTDP1ALDH1A1AOC3 | |
| SCHEMBL10262594 | 0.83 | LTA4H (0.47) | CYP3A4SMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL24403990 | 0.82 | MAPT (0.39) | SMN1; SMN2MAPTTDP1L3MBTL1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653615-B1 | CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2023-03-01 | — | — | EP | disclosed |
| EP-3653615-A1 | CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION | Tokuyama Corporation (JP) | 2020-05-20 | — | — | EP | disclosed |