Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25954061 | 1.00 | ELANE (0.46) | ELANECA1CA2CA12CA7 | |
| SCHEMBL25954134 | 0.94 | ELANE (0.42) | ELANECA1CA2CA12CA7 | |
| SCHEMBL25954108 | 0.94 | LTA4H (0.48) | ELANECA1CA2CA12CA7 | |
| SCHEMBL25954058 | 0.94 | LTA4H (0.48) | ELANECA1CA2CA12CA7 | |
| SCHEMBL25954105 | 0.94 | ESR2 (0.48) | ELANECA1CA2CA12CA7 | |
| SCHEMBL4568709 | 0.93 | ACHE (0.54) | ELANECA1CA2CA12CA7 | |
| SCHEMBL12206421 | 0.93 | LTA4H (0.52) | ELANECA1CA2CA12CA7 | |
| SCHEMBL1011203 | 0.93 | KIF11 (0.45) | ELANESMN1; SMN2LMNALTA4HCES2 | |
| SCHEMBL25954113 | 0.93 | ELANE (0.45) | ELANECA1CA2CA12CA7 | |
| SCHEMBL9042759 | 0.91 | AHR (0.50) | ELANEAOC3MAPTHSD11B1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031096-A1 | PIPERAZINE DERIVATIVES USEFUL AS HYPOGLYCEMIC AGENTS | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | claimed |
| US-6444860-B1 | — | — | None | — | — | US | disclosed |
| WO-2026047423-A1 | COLOURED PHOTOCHROMIC COSMETIC INGREDIENT FOR COSMETIC COMPOSITIONS CHANGING COLOUR WHEN IRRADIATED WITH ULTRAVIOLET LIGHT, AND METHOD FOR THE PREPARATION THEREOF | INTERCOS S.P.A. (IT) | 2026-03-05 | — | — | WO | disclosed |
| US-12344617-B2 | Indolonaphthopyrans | TRANSITIONS OPTICAL, LTD. (IE) | 2025-07-01 | — | — | US | disclosed |
| CN-113227098-B | Indolonaphthopyrans | 光学转变有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-114031595-B | Photochromic compound and application thereof | 江苏视科新材料股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| EP-2545095-B1 | METHODS FOR PRODUCING PHOTOSENSITIVE MICROPARTICLES, NON-AQUEOUS DISPERSIONS THEREOF AND ARTICLES PREPARED THEREWITH | TRANSITIONS OPTICAL INC (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-4289831-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND EYEGLASSES | Hoya Lens Thailand Ltd. (TH) | 2023-12-13 | — | — | EP | disclosed |
| WO-2023220461-A1 | PHOTOINITIATORS, COMPOSITIONS, AND METHODS OF FORMING AN OBJECT | QUADRATIC 3D, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-20230359068-A1 | OPTICAL ARTICLE, SPECTACLES, AND PHOTOCHROMIC COMPOUND | HOYA LENS THAILAND LTD. (TH) | 2023-11-09 | — | — | US | disclosed |
| US-5514817-A | PHOTOCHROMIC | PPG INDUSTRIES, INC. (US) | 1996-05-07 | — | — | US | disclosed |
| WO-1996004576-A1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG INDUSTRIES, INC. (US) | 1996-02-15 | — | — | WO | disclosed |
| EP-0691965-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1996-01-17 | — | — | EP | disclosed |
| US-5458814-A | Ophthalmic lenses | TRANSITIONS OPTICAL, INC. (US) | 1995-10-17 | — | — | US | disclosed |
| WO-1995016215-A1 | NOVEL SUBSTITUTED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1995-06-15 | — | — | WO | disclosed |
| US-5411679-A | REVERSIBLE PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 1995-05-02 | — | — | US | disclosed |
| WO-1995005371-A1 | PHOTOCHROMIC NAPHTHO(2,1-B)PYRANS | PILKINGTON PLC (GB) | 1995-02-23 | — | — | WO | disclosed |
| WO-1995005382-A1 | PHOTOCHROMIC HETEROCYCLOCHROMENES | PILKINGTON PLC (GB) | 1995-02-23 | — | — | WO | disclosed |
| WO-1994022850-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1994-10-13 | — | — | WO | disclosed |
| WO-1994020869-A1 | NOVEL BENZOPYRANS | PPG INDUSTRIES, INC. (US) | 1994-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12344617-B2 | Indolonaphthopyrans | TPH1, TPH2, IDO1 | ELANE 4649/4885CA1 4619/4885CA2 4327/4885 |
| US-20230359068-A1 | OPTICAL ARTICLE, SPECTACLES, AND PHOTOCHROMIC COMPOUND | GRK1, TCOF1, ARPC1B | ELANE 4567/4885CA1 1898/4885CA2 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.