Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 12/20 | 0.61 |
| ▸ | PLAT | P00750 | 10/20 | 0.61 |
| ▸ | F2 | P00734 | 9/20 | 0.61 |
| ▸ | PLG | P00747 | 10/20 | 0.60 |
| ▸ | F10 | P00742 | 2/20 | 0.55 |
| ▸ | KLK8 | O60259 | 1/20 | 0.55 |
| ▸ | KLK2 | P20151 | 1/20 | 0.55 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.55 |
| ▸ | CTSC | P53634 | 1/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | LAP3 | P28838 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21950823 | 0.83 | PLAU (0.57) | PLAUPLATF2PLGF10 | |
| SCHEMBL19614989 | 0.81 | PLAU (0.65) | PLAUPLATF2PLGF10 | |
| SCHEMBL7403534 | 0.79 | F2 (0.86) | PLAUPLATF2PLGF10 | |
| SCHEMBL10723196 | 0.77 | LNPEP (0.54) | LAP3 | |
| SCHEMBL10723878 | 0.77 | LNPEP (0.54) | LAP3 | |
| SCHEMBL10723771 | 0.77 | LNPEP (0.54) | LAP3 | |
| SCHEMBL10728376 | 0.77 | LNPEP (0.54) | LAP3 | |
| SCHEMBL21950806 | 0.77 | CTSS (0.59) | PLAUPLATF2PLG | |
| SCHEMBL2245466 | 0.76 | PLAU (0.77) | PLAUPLATF2PLGF10 | |
| SCHEMBL2249441 | 0.76 | PLAU (1.00) | PLAUPLATF2PLGF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653215-A1 | THERANOSTIC INHIBITORS AND ACTIVITY-BASED PROBES FOR THE KLK7 PROTEASE | University of Patras (GR) | 2020-05-20 | — | — | EP | disclosed |